PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34750375-5 2021 TCP1 showed higher expression in the adriamycin-resistant leukemia cell line HL60/A and K562/A, comparing to their respective parent cells HL60 and K562 cells. Doxorubicin 37-47 t-complex 1 Homo sapiens 0-4 34750375-9 2021 Pharmacological inhibition of AKT/mTOR signal particularly activated autophagy and resensitized TCP1-overexpressing HL60 cells to adriamycin. Doxorubicin 130-140 t-complex 1 Homo sapiens 96-100 34750375-7 2021 Mechanistic investigations revealed that TCP1 inhibited autophagy and adriamycin-induced cell apoptosis, and TCP1-mediated autophagy inhibition conferred resistance to adriamycin-induced cell apoptosis. Doxorubicin 70-80 t-complex 1 Homo sapiens 41-45 34750375-7 2021 Mechanistic investigations revealed that TCP1 inhibited autophagy and adriamycin-induced cell apoptosis, and TCP1-mediated autophagy inhibition conferred resistance to adriamycin-induced cell apoptosis. Doxorubicin 168-178 t-complex 1 Homo sapiens 109-113