PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17483339-1	2007	Doxorubicin treatment was found to augment the expression of the extracellular matrix (ECM) protein fibulin-1 in cultured human breast cancer cell lines and in MDA-MB-361 tumors grown in athymic mice.	Doxorubicin	0-11	fibulin 1	Homo sapiens	100-109	
17483339-2	2007	Doxorubicin was also found to augment tumor expression of the fibulin-1-binding proteins fibronectin and laminin-1.	Doxorubicin	0-11	fibulin 1	Homo sapiens	62-71	
17483339-3	2007	Growth of breast cancer cell lines on Matrigel, an ECM extract containing fibulin-1 and laminin-1, resulted in lower levels of doxorubicin-induced apoptosis as compared with controls.	Doxorubicin	127-138	fibulin 1	Homo sapiens	74-83	
17483339-5	2007	Monoclonal antibodies against fibulin-1 reversed Matrigel-dependent doxorubicin resistance.	Doxorubicin	68-79	fibulin 1	Homo sapiens	30-39	
17483339-6	2007	Furthermore, small interfering RNA-mediated suppression of fibulin-1 expression in breast cancer cells resulted in a 10-fold increase in doxorubicin sensitivity as compared with control cells.	Doxorubicin	137-148	fibulin 1	Homo sapiens	59-68