PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29204687-7 2018 RESULTS: In vitro, zoptarelin doxorubicin inhibits the drug transporters organic anion-transporting polypeptide 1B3 (OATP1B3) and organic cation transporter 2 (OCT2). Doxorubicin 30-41 solute carrier organic anion transporter family member 1B3 Homo sapiens 73-115 29204687-7 2018 RESULTS: In vitro, zoptarelin doxorubicin inhibits the drug transporters organic anion-transporting polypeptide 1B3 (OATP1B3) and organic cation transporter 2 (OCT2). Doxorubicin 30-41 solute carrier organic anion transporter family member 1B3 Homo sapiens 117-124 27777271-6 2017 Interestingly, transwell assays using Madin-Darby canine kidney II cell line cells stably expressing specific uptake and/or efflux transporters revealed that OATP1B1, OATP1B3, and OATP1A2, either alone or in combination with MDR1, significantly transported doxorubicin. Doxorubicin 257-268 solute carrier organic anion transporter family member 1B3 Homo sapiens 167-174 24554572-10 2014 Interestingly, transgenic liver-specific expression of human OATP1A2, OATP1B1 or OATP1B3 could partially rescue the increased doxorubicin plasma levels of Oatp1a/1b(-/-) mice. Doxorubicin 126-137 solute carrier organic anion transporter family member 1B3 Homo sapiens 81-88 24554572-11 2014 Hepatic uptake and bile-derived intestinal excretion of doxorubicin were completely reverted to wild-type levels by OATP1A2, and partially by OATP1B1 and OATP1B3. Doxorubicin 56-67 solute carrier organic anion transporter family member 1B3 Homo sapiens 154-161 34230586-5 2021 We identified two poorly characterized, human-specific transporters (SLCO1A2, SLCO1B3) whose loss of function protects against doxorubicin-cardiotoxicity, but does not affect cell death in cancer cells. Doxorubicin 127-138 solute carrier organic anion transporter family member 1B3 Homo sapiens 78-85