PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23503641-0 2013 Knockdown of DEPTOR induces apoptosis, increases chemosensitivity to doxorubicin and suppresses autophagy in RPMI-8226 human multiple myeloma cells in vitro. Doxorubicin 69-80 DEP domain containing MTOR interacting protein Homo sapiens 13-19 23503641-11 2013 The downregulation of DEPTOR inhibited proliferation, enhanced the doxorubicin-induced growth inhibitory effects on RPMI-8226 cells, and increased the expression of cleaved caspase-3 and cleaved poly(ADP-ribose) polymerase (PARP). Doxorubicin 67-78 DEP domain containing MTOR interacting protein Homo sapiens 22-28 23503641-13 2013 In conclusion, our data demonstrated that the downregulation of DEPTOR induces apoptosis, increases chemosensitivity to doxorubicin, and suppresses autophagy and the activation of the PI3K/Akt signaling pathway in RPMI-8226 human multiple myeloma cells. Doxorubicin 120-131 DEP domain containing MTOR interacting protein Homo sapiens 64-70