PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31093684-0	2019	Acylated ghrelin prevents doxorubicin-induced cardiac intrinsic cell death and fibrosis in rats by restoring IL-6/JAK2/STAT3 signaling pathway and inhibition of STAT1.	Doxorubicin	26-37	Janus kinase 2	Rattus norvegicus	114-118	
32711244-0	2020	Fucoidan from Fucus vesiculosus attenuates doxorubicin-induced acute cardiotoxicity by regulating JAK2/STAT3-mediated apoptosis and autophagy.	Doxorubicin	43-54	Janus kinase 2	Rattus norvegicus	98-102	
32711244-10	2020	Additionally, western blotting revealed DOX-induced JAK2/STAT3 pathway activation, which was enhanced by fucoidan and weaken by AG490.	Doxorubicin	40-43	Janus kinase 2	Rattus norvegicus	52-56	
32711244-11	2020	Hence, fucoidan exerted a favorable effect on DOX-induced cardiotoxicity by enhancing autophagy and suppressing apoptosis in a JAK2/STAT3-dependent manner, which may provide a promising and novel therapeutic strategy against negative chemotherapy-induced effects.	Doxorubicin	46-49	Janus kinase 2	Rattus norvegicus	127-131