PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14975762-2	2004	Doxorubicin depletes cardiac p300, a transcriptional coactivator that is required for the maintenance of the differentiated phenotype of cardiac myocytes.	Doxorubicin	0-11	E1A binding protein p300	Mus musculus	29-33	
14975762-4	2004	Transgenic mice overexpressing p300 in the heart and wild-type mice were subjected to doxorubicin treatment.	Doxorubicin	86-97	E1A binding protein p300	Mus musculus	31-35	
14975762-8	2004	These findings demonstrate that overexpression of p300 protects cardiac myocytes from doxorubicin-induced apoptosis and reduces the extent of acute heart failure in adult mice in vivo.	Doxorubicin	86-97	E1A binding protein p300	Mus musculus	50-54	
7651731-4	1995	Keratinocytes transfected with the mutant d1787N (which binds to p60, p105, p107 and p300) showed a lethality in response to CDDP (10 micrograms ml-1) fourfold higher than controls and threefold higher in response to DOX and radiation (5 grays).	Doxorubicin	217-220	E1A binding protein p300	Mus musculus	85-89