PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16061816-2	2005	We demonstrate this approach by recombining the genes coding for TEM1 beta-lactamase (BLA) and the Escherichia coli maltose binding protein (MBP) to create a family of MBP-BLA hybrids in which maltose is a positive or negative effector of beta-lactam hydrolysis.	Maltose	193-200	TEM-1 beta-lactamase	Escherichia coli	65-84	
15555998-2	2004	The gene encoding TEM1 beta-lactamase was circularly permuted in a random fashion and subsequently randomly inserted into the gene encoding Escherichia coli maltose binding protein.	Maltose	157-164	TEM-1 beta-lactamase	Escherichia coli	18-37	
14741221-7	2004	For one of these enzymes, the presence of maltose increased k(cat) by 70% and k(cat)/K(m) by 80% and resulted in kinetic parameters that were almost identical to TEM-1 beta-lactamase.	Maltose	42-49	TEM-1 beta-lactamase	Escherichia coli	162-182