PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22964465-5	2012	Endothelin-1 (2 nM)-induced inhibition of NA release was neither attenuated by PLC inhibitors [U-73122 (3 muM) and ET-18-OCH(3) (3 muM)] nor by Ca(2+)-activated K(+) channel blockers [charybdotoxin (0.1 muM) (a blocker of BK type K(+) channel) and apamin (0.3 muM) (a blocker of SK type K(+) channel)].	Charybdotoxin	184-197	endothelin 1	Rattus norvegicus	0-12	
9612301-2	1998	Using the whole cell patch-clamp technique in rat intrapulmonary arterial smooth muscle cells, we found that ET-1 and the voltage-dependent K+ (Kv)-channel antagonist 4-aminopyridine, but not the Ca(2+)-activated K(+)-channel antagonist charybdotoxin (ChTX), caused membrane depolarization.	Charybdotoxin	237-250	endothelin 1	Rattus norvegicus	109-113	
9612301-2	1998	Using the whole cell patch-clamp technique in rat intrapulmonary arterial smooth muscle cells, we found that ET-1 and the voltage-dependent K+ (Kv)-channel antagonist 4-aminopyridine, but not the Ca(2+)-activated K(+)-channel antagonist charybdotoxin (ChTX), caused membrane depolarization.	Charybdotoxin	252-256	endothelin 1	Rattus norvegicus	109-113	
9612301-3	1998	In the presence of 100 nM ChTX, ET-1 (10(-10) to 10(-7) M) caused a concentration-dependent inhibition of K+ current (56.2 +/- 3.8% at 10(-7) M) and increased the rate of current inactivation.	Charybdotoxin	26-30	endothelin 1	Rattus norvegicus	32-36	
9231761-12	1997	The ET-1 activated large-conductance Ca2+-dependent K+ (BK(Ca)) channels were blocked by 20 mM tetraethylammonium but were insensitive to the K+ channel blockers apamin (1 microM), charybdotoxin (200 nM), or iberiotoxin (200 nM).	Charybdotoxin	181-194	endothelin 1	Rattus norvegicus	4-8