PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8895200-2 1996 The PKC activator 12-O-tetradecanoylphorbol-13-acetate (TPA) reduced daunomycin accumulation in both drug-sensitive KB-3-1 and MDR KB-C1 cells in a time-dependent manner. Daunorubicin 69-79 proline rich transmembrane protein 2 Homo sapiens 4-7 8895200-8 1996 We therefore propose that the TPA-induced reduction in daunomycin accumulation in KB cells is due to a PKC-mediated process, which is maintained after depletion of certain PKC subspecies or is due to activation of downregulation insensitive PKC subspecies. Daunorubicin 55-65 proline rich transmembrane protein 2 Homo sapiens 103-106