PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9685063-8	1998	Daunorubicin applied in combination with G-CSF at 5 ng/ml or with IL-3 at 0.5 ng/ml exerted a significantly higher degree of cytotoxicity on normal hematopoietic progenitor cells, resulting in 21% and 30% surviving colonies as compared with the 38% recorded for daunorubicin alone (P < 0.05).	Daunorubicin	262-274	interleukin 3	Homo sapiens	66-70	
15380050-7	2004	The effect of G-CSF, GM-CSF, IL3 and M-CSF on daunorubicin mediated cytotoxicity in K562 cells was measured using the MTT assay.	Daunorubicin	46-58	interleukin 3	Homo sapiens	29-32	
11498841-0	1999	[Study on the sensitization of acute myeloid leukemia cell to daunorubicin by recombinant human interleukin-3].	Daunorubicin	62-74	interleukin 3	Homo sapiens	96-109	
11498841-1	1999	OBJECTIVE: To evaluate the effect of recombinant human interleukin-3(rhIL-3) on the sensitization of acute myeloid leukemia(AML) cells to daunorubicin(DNR).	Daunorubicin	138-150	interleukin 3	Homo sapiens	55-68	
9685063-11	1998	We conclude that G-CSF and IL-3 augment the effect of daunorubicin on normal hematopoietic progenitor cells.	Daunorubicin	54-66	interleukin 3	Homo sapiens	27-31	
8599980-9	1996	G-CSF significantly enhanced the cytotoxic effect of daunorubicin, mitoxantrone, etoposide and Ara-C by 20-40%, which GM-CSF and IL-3 showed a significantly increased toxicity for Ara-C only.	Daunorubicin	53-65	interleukin 3	Homo sapiens	129-133	
9180292-1	1997	In the present study it was investigated whether and by which mechanisms the co-administration of interleukin-3 (IL-3) and the P-glycoprotein blocker PSC 833 can augment mitoxantrone (MX) and daunorubicin (DAU) cytotoxicity in two human growth factor dependent P-glycoprotein (P-gp) positive myeloid leukemic cell lines, Mo-7 and GF-D8.	Daunorubicin	192-204	interleukin 3	Homo sapiens	98-111	
9180292-1	1997	In the present study it was investigated whether and by which mechanisms the co-administration of interleukin-3 (IL-3) and the P-glycoprotein blocker PSC 833 can augment mitoxantrone (MX) and daunorubicin (DAU) cytotoxicity in two human growth factor dependent P-glycoprotein (P-gp) positive myeloid leukemic cell lines, Mo-7 and GF-D8.	Daunorubicin	192-204	interleukin 3	Homo sapiens	113-117	
9180292-3	1997	Increased cytotoxicity occurred in Mo-7 cells preincubated with 24h IL-3 followed by 1 h MX (cell survival: 85% +/- 6 vs 68% +/- 2, at 0.05 microM MX, P < 0.005) or DAU (79% +/- 8 vs 62% +/- 9 at 0.8 microg/ml DAU, P < 0.05).	Daunorubicin	168-171	interleukin 3	Homo sapiens	68-72	
9180292-3	1997	Increased cytotoxicity occurred in Mo-7 cells preincubated with 24h IL-3 followed by 1 h MX (cell survival: 85% +/- 6 vs 68% +/- 2, at 0.05 microM MX, P < 0.005) or DAU (79% +/- 8 vs 62% +/- 9 at 0.8 microg/ml DAU, P < 0.05).	Daunorubicin	213-216	interleukin 3	Homo sapiens	68-72	
9180292-8	1997	The administration of IL-3 plus PSC 833 in the Mo-7 cell line resulted in an additive effect on DAU cytotoxicity.	Daunorubicin	96-99	interleukin 3	Homo sapiens	22-26	
9180292-9	1997	At 0.8 microg/ml DAU and 2 microg/ml PSC 833, the percentage surviving cells decreased from 62% +/- 9 in the absence of IL-3 to 37% +/- 3 in the presence of IL-3 (P < 0.01).	Daunorubicin	17-20	interleukin 3	Homo sapiens	120-124	
9180292-9	1997	At 0.8 microg/ml DAU and 2 microg/ml PSC 833, the percentage surviving cells decreased from 62% +/- 9 in the absence of IL-3 to 37% +/- 3 in the presence of IL-3 (P < 0.01).	Daunorubicin	17-20	interleukin 3	Homo sapiens	157-161	
9180292-12	1997	In summary, the results demonstrate that the combined administration of IL-3 and PSC 833 can enhance the cytotoxic effects of DAU but not MX in these P-gp positive cell lines whereas the effects of MX could be modulated by factors which influence topo II activity.	Daunorubicin	126-129	interleukin 3	Homo sapiens	72-76	
1391803-0	1992	Comparative effects of G-CSF, GM-CSF and IL-3 on cytosine arabinoside- and daunorubicin-mediated cytotoxicity of acute myeloid leukemia cells and normal myeloid progenitors.	Daunorubicin	75-87	interleukin 3	Homo sapiens	41-45