PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18322072-4	2008	In our search for potential biomarkers for the occurrence of this side effect, we examined the activity of recombinant aldo-keto reductase enzymes, aldo-keto reductase (AKR) 1A1 and AKR1C2, with DAUN and DOX as substrates.	Daunorubicin	195-199	aldo-keto reductase family 1 member A1	Homo sapiens	148-177	
7632166-4	1995	The other drugs--haloperidol, metyrapone, loxoprofen, daunorubicin and acetohexamide--were highly reduced by carbonyl reductase and/or aldehyde reductase.	Daunorubicin	54-66	aldo-keto reductase family 1 member A1	Homo sapiens	135-153	
32588086-4	2020	In the present study, we investigated the influence of these anticancer drugs on the reductive Dau metabolism mediated by the aldo-keto reductases AKR1A1, 1B10, 1C3, and 7A2 and carbonyl reductase 1 (CBR1).	Daunorubicin	95-98	aldo-keto reductase family 1 member A1	Homo sapiens	147-153	
22982121-2	2012	To better understand the individual importance of each enzyme in the reduction and to provide deeper insight into the binding at atomic level we performed molecular docking and dynamics simulations of DAUN and DOX into the active sites of human carbonyl reductase 1 (CBR1) and human aldehyde reductase (AKR1A1).	Daunorubicin	201-205	aldo-keto reductase family 1 member A1	Homo sapiens	283-301	
22982121-2	2012	To better understand the individual importance of each enzyme in the reduction and to provide deeper insight into the binding at atomic level we performed molecular docking and dynamics simulations of DAUN and DOX into the active sites of human carbonyl reductase 1 (CBR1) and human aldehyde reductase (AKR1A1).	Daunorubicin	201-205	aldo-keto reductase family 1 member A1	Homo sapiens	303-309