PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19914848-1 2010 We examined the effect of the anthracyclines aclarubicin, bleomycin, daunorubicin, doxorubicin and idarubicin on human gamma- and beta-globin promoter activity in an in vitro luciferase assay, ex vivo in erythroid cultures and in vivo in transgenic mice carrying the human gamma-globin gene. Daunorubicin 69-81 hemoglobin subunit gamma 1 Homo sapiens 119-141 19914848-5 2010 Daunorubicin induced HbF in thalassaemic cells ex vivo with the highest statistical significance and, importantly and in contrast to the clinical HbF inducer hydroxyurea, showed specific induction of gamma-globin without associated induction of alpha-globin. Daunorubicin 0-12 hemoglobin subunit gamma 1 Homo sapiens 200-212 19914848-6 2010 Daunorubicin was screened in transgenic mice carrying the human (A)gamma-globin gene, and it resulted in increased (A)gamma-globin mRNA levels. Daunorubicin 0-12 hemoglobin subunit gamma 1 Homo sapiens 64-79 19914848-6 2010 Daunorubicin was screened in transgenic mice carrying the human (A)gamma-globin gene, and it resulted in increased (A)gamma-globin mRNA levels. Daunorubicin 0-12 hemoglobin subunit gamma 1 Homo sapiens 65-79