PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34963561-4	2022	In addition, DNR induced NOX4-dependent ROS production, leading to the activation of p38 MAPK and inactivation of Akt and ERK.	Daunorubicin	13-16	mitogen-activated protein kinase 1	Homo sapiens	122-125	
34963561-11	2022	Cumulatively, our data indicate that DNR induces MCL1 downregulation in K562 cells by promoting p38 MAPK-mediated dephosphorylation of CREB and inhibiting the Akt-ERK axis-mediated Sp1 protein stabilization.	Daunorubicin	37-40	mitogen-activated protein kinase 1	Homo sapiens	163-166	
21176351-1	2010	The study was aimed to investigate the effects of bortezomib (BTZ) on the expression of ERK, JNK and P38 in daunorubicin (DNR)-resistant K562 cells (K562/DNR) and to clarify the molecular mechanism of BTZ in reversing the drug-resistance in leukemic cells.	Daunorubicin	108-120	mitogen-activated protein kinase 1	Homo sapiens	88-91	
21729547-0	2011	[Effect of different concentrations of bortezomib on the expression of ERK, JNK and P38 in daunorubicin-resistant K562 cells].	Daunorubicin	91-103	mitogen-activated protein kinase 1	Homo sapiens	71-74	
21729547-1	2011	The aim of this study was to investigate the effect of proteasome inhibitor bortezomib on the expression of ERK, JNK, and P38 in daunorubicin (DNR)-resistant K562 cells and its mechanism.	Daunorubicin	129-141	mitogen-activated protein kinase 1	Homo sapiens	108-111	
20001229-6	2010	DMPH decreased the phosphorylation of ERK and inhibited daunorubicin-induced ERK activation.	Daunorubicin	56-68	mitogen-activated protein kinase 1	Homo sapiens	77-80