PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25986678-9 2015 Both flavopiridol and SNS-032 showed synergistic antiproliferative effects in combination with relevant ABC transporter substrates such as daunorubicin and topotecan in cancer cells. Daunorubicin 139-151 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 104-107 30826329-0 2019 Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters. Daunorubicin 93-105 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 179-182 30826329-3 2019 This phenomenon is often caused by pharmacokinetic mechanisms such as efflux of DAUN from cancer cells through ATP-binding cassette (ABC) transporters and its conversion to less cytostatic but more cardiotoxic daunorubicinol (DAUN-OL) by carbonyl reducing enzymes (CREs). Daunorubicin 80-84 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 111-131 30826329-3 2019 This phenomenon is often caused by pharmacokinetic mechanisms such as efflux of DAUN from cancer cells through ATP-binding cassette (ABC) transporters and its conversion to less cytostatic but more cardiotoxic daunorubicinol (DAUN-OL) by carbonyl reducing enzymes (CREs). Daunorubicin 80-84 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 133-136 30339824-1 2019 In the present study, the molecular docking mechanism based on pharmacodynamic interactions between the ligands AZD1208 and recognized chemotherapy agents (Vincristine and Daunorubicin) with human ATP-binding cassette (ABC) transporters (ABCB1) was investigated. Daunorubicin 172-184 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 197-217 30339824-1 2019 In the present study, the molecular docking mechanism based on pharmacodynamic interactions between the ligands AZD1208 and recognized chemotherapy agents (Vincristine and Daunorubicin) with human ATP-binding cassette (ABC) transporters (ABCB1) was investigated. Daunorubicin 172-184 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 219-222