PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26861753-4 2016 OCT1 downregulation by shRNA impaired daunorubicin uptake into the TOV2223G cells, and these cells were significantly more resistant to the drug in comparison to the control shRNA. Daunorubicin 38-50 solute carrier family 22 member 1 Homo sapiens 0-4 26861753-0 2016 The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin. Daunorubicin 95-107 solute carrier family 22 member 1 Homo sapiens 37-41 26861753-3 2016 Using the high-grade serous ovarian cancer cell line TOV2223G, we show that OCT1 mediated the high affinity (Km ~ 5 muM) uptake of daunorubicin into the cells, and that micromolar amounts of choline completely abolished the drug entry. Daunorubicin 131-143 solute carrier family 22 member 1 Homo sapiens 76-80