PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31383893-8 2019 Additionally, niclosamide reversed adipocyte-induced EMT with a correlated inhibition of IL-6/Stat3 activation and downregulation of EMT-TFs TWIST and SNAIL. Niclosamide 14-25 snail family transcriptional repressor 1 Homo sapiens 151-156 30143678-4 2018 In addition, we showed that niclosamide inhibits the epithelial-to-mesenchymal transition (EMT), migration and colony formation of the OSCC cells, by dose-dependently upregulating E-cadherin and the tissue inhibitor of metalloproteinases 2 (TIMP2) mRNA levels, while reducing the expression levels of vimentin, snail, MMP2 and MMP9 mRNA. Niclosamide 28-39 snail family transcriptional repressor 1 Homo sapiens 311-316 28418862-4 2017 In this study, we show that niclosamide directly targets Axin-GSK3 interaction, at least in part, resulting in suppression of Wnt/Snail-mediated EMT. Niclosamide 28-39 snail family transcriptional repressor 1 Homo sapiens 130-135 28418862-6 2017 Niclosamide treatment successfully attenuates Snail abundance while increasing E-cadherin abundance in xenograft tumor. Niclosamide 0-11 snail family transcriptional repressor 1 Homo sapiens 46-51 28418865-3 2017 In the accompanying report, we show that the anti-helminthic niclosamide directly binds to GSK-3 and inhibits Axin functions in colon cancer cells, with reversion of Snail-mediated epithelial-mesenchymal transition. Niclosamide 61-72 snail family transcriptional repressor 1 Homo sapiens 166-171 28418865-6 2017 Further, niclosamide activates Raf-1 kinase inhibitory protein, a downstream target of Snail repressor. Niclosamide 9-20 snail family transcriptional repressor 1 Homo sapiens 87-92 27449264-10 2016 ZSTK474 and niclosamide also reversed EMT markers and EMT-inducing proteins including Snail, Slug, Twist and CEACAM6 in WSTF-overexpressing A549 cells. Niclosamide 12-23 snail family transcriptional repressor 1 Homo sapiens 86-91 26810188-8 2016 In addition, niclosamide reversed the EMT phenotype of 231-CR by downregulation of snail and vimentin. Niclosamide 13-24 snail family transcriptional repressor 1 Homo sapiens 83-88 22799185-0 2012 [Effect of snail control of niclosamide by soil mixing and spraying methods in high dam of terrace]. Niclosamide 28-39 snail family transcriptional repressor 1 Homo sapiens 11-16 22799185-1 2012 The snail control efffect of niclosamide by soil mixing and spraying method were compared, and the results showed that the effects of the two methods were similar. Niclosamide 29-40 snail family transcriptional repressor 1 Homo sapiens 4-9 21752808-1 2012 Currently schistosomiasis transmission has been suppressed to low levels in many historically endemic areas of China by widespread use of praziquantel in human and bovine populations and application of niclosamide for snail control. Niclosamide 202-213 snail family transcriptional repressor 1 Homo sapiens 218-223 18454287-2 2008 Currently, only one chemical molluscicide, niclosamide, which is used as 50% wettable powder of niclosamide ethanolamine salt (WPN), is commercially available for field snail control in China. Niclosamide 43-54 snail family transcriptional repressor 1 Homo sapiens 169-174 2128985-6 1990 Beginning in 1986 niclosamide was applied focally wherever infected snails were found and the monthly snail surveillance continued until 1989. Niclosamide 18-29 snail family transcriptional repressor 1 Homo sapiens 68-73 34572856-0 2021 Niclosamide and Pyrvinium Are Both Potential Therapeutics for Osteosarcoma, Inhibiting Wnt-Axin2-Snail Cascade. Niclosamide 0-11 snail family transcriptional repressor 1 Homo sapiens 97-102 34572856-5 2021 In this study, we show that both niclosamide and pyrvinium target Axin2, resulting in the suppression of EMT by the inhibition of the Wnt/Snail axis in osteosarcoma cells. Niclosamide 33-44 snail family transcriptional repressor 1 Homo sapiens 138-143 3704470-5 1986 Bayluscide was applied in two different ways depending on snail distribution within the sites. Niclosamide 0-10 snail family transcriptional repressor 1 Homo sapiens 58-63