PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24750999-0 2014 Niclosamide enhances ROS-mediated cell death through c-Jun activation. Niclosamide 0-11 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 53-58 24750999-8 2014 Niclosamide pretreatment also induced c-Jun and its phosphorylation in the presence of H2O2, thereby enhancing apoptosis. Niclosamide 0-11 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 38-43 24750999-10 2014 Knockdown of c-Jun also decreased PARP cleavage and clonogenic cell survival in niclosamide- and IR-treated H1299 cells. Niclosamide 80-91 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 13-18 24750999-11 2014 Our findings suggest that niclosamide could be a promising radiosensitizer in lung cancer patients through activation of the p38 MAPK-c-Jun axis. Niclosamide 26-37 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 134-139 26118906-10 2015 Analysis of niclosamide"s effect on 11 cancer-related signal pathway reporters reveals that three of them, the E2F1, AP1, and c-Myc-responsive reporters, are significantly inhibited. Niclosamide 12-23 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 117-120