PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10528214-2	1999	Here, we show that in HL60 cells, vincristine, a microtubule-disrupting agent that induces a strong production of IL-1, triggers the activation of both extracellular signal-related kinase (ERK) and c-Jun N-terminal kinase (JNK-1).	Vincristine	34-45	mitogen-activated protein kinase 1	Homo sapiens	152-187	
35614948-0	2022	Vincristine Promotes Transdifferentiation of Fibroblasts Into Myofibroblasts via P38 and ERK Signal Pathways.	Vincristine	0-11	mitogen-activated protein kinase 1	Homo sapiens	81-84	
35614948-0	2022	Vincristine Promotes Transdifferentiation of Fibroblasts Into Myofibroblasts via P38 and ERK Signal Pathways.	Vincristine	0-11	mitogen-activated protein kinase 1	Homo sapiens	89-92	
26232556-0	2015	Erythropoietin protects neuroblastoma cells against etoposide and vincristine by activating ERK and AKT pathways but has no effect in kidney cells.	Vincristine	66-77	mitogen-activated protein kinase 1	Homo sapiens	92-95	
10623471-3	2000	All four agents tested (vinblastine, vincristine, Taxol, and colchicine) caused significant (6- to 13-fold) activation of JNK, concomitant inactivation of ERK, and a reduction in basal p38 MAPK activity.	Vincristine	37-48	mitogen-activated protein kinase 1	Homo sapiens	155-158	
10623471-3	2000	All four agents tested (vinblastine, vincristine, Taxol, and colchicine) caused significant (6- to 13-fold) activation of JNK, concomitant inactivation of ERK, and a reduction in basal p38 MAPK activity.	Vincristine	37-48	mitogen-activated protein kinase 1	Homo sapiens	189-193	
31770526-4	2020	More interestingly, we showed for the first time that among inhibitors of different signaling pathways including those targeting PI3K, ERK, and NF-kappaB, the enhancive effect of small molecule inhibitor of c-Myc 10058-F4 was more significant on VCR cytotoxicity.	Vincristine	246-249	mitogen-activated protein kinase 1	Homo sapiens	135-138	
10528214-2	1999	Here, we show that in HL60 cells, vincristine, a microtubule-disrupting agent that induces a strong production of IL-1, triggers the activation of both extracellular signal-related kinase (ERK) and c-Jun N-terminal kinase (JNK-1).	Vincristine	34-45	mitogen-activated protein kinase 1	Homo sapiens	189-192	
10528214-4	1999	Each kind of the nonreceptor tyrosine kinase blockers efficiently inhibits the vincristine-induced IL-1 production and diminishes the level of IL-1 transcripts, indicating that the ERK and JNK pathways act coordinately to elicit the transcription of the IL-1 gene.	Vincristine	79-90	mitogen-activated protein kinase 1	Homo sapiens	181-184