PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30710045-0 2019 Glycine Exhibits Neuroprotective Effects in Ischemic Stroke in Rats through the Inhibition of M1 Microglial Polarization via the NF-kappaB p65/Hif-1alpha Signaling Pathway. Glycine 0-7 hypoxia inducible factor 1 subunit alpha Rattus norvegicus 143-153 34901821-0 2021 HIF-1alpha overexpression in mesenchymal stem cell-derived exosome-encapsulated arginine-glycine-aspartate (RGD) hydrogels boost therapeutic efficacy of cardiac repair after myocardial infarction. Glycine 89-96 hypoxia inducible factor 1 subunit alpha Rattus norvegicus 0-10 30710045-8 2019 We show that glycine suppresses Hif-1alpha by inhibiting the upregulation of NF-kappaB p65 after ischemia-reperfusion injury, resulting in the inhibition of proinflammatory activity. Glycine 13-20 hypoxia inducible factor 1 subunit alpha Rattus norvegicus 32-42 30710045-9 2019 The activation of AKT mediates the inhibition of NF-kappaB p65/Hif-1alpha signaling by glycine. Glycine 87-94 hypoxia inducible factor 1 subunit alpha Rattus norvegicus 63-73 30710045-12 2019 Taken together, our findings provide a new understanding of glycine in neuroprotection by inhibiting M1 microglial polarization and promoting anti-inflammation by suppressing NF-kappaB p65/Hif-1alpha signaling. Glycine 60-67 hypoxia inducible factor 1 subunit alpha Rattus norvegicus 189-199