PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27518042-4 2016 The co-repression occurs through binding of TDP-43 to mRNA(s) at specific UG/GU sequences and recruitment of the inhibitory CYFIP1-FMRP complex by its glycine-rich domain. Glycine 151-158 fragile X messenger ribonucleoprotein 1 Homo sapiens 131-135 26374839-2 2015 FMRP uses an arginine-glycine-rich (RGG) motif for specific interactions with guanine (G)-quadruplexes, mRNA elements implicated in the disease-associated regulation of specific mRNAs. Glycine 22-29 fragile X messenger ribonucleoprotein 1 Homo sapiens 0-4 25416280-2 2015 FMRP is a selective RNA binding protein owing to two central K-homology domains and a C-terminal arginine-glycine-glycine (RGG) box. Glycine 106-113 fragile X messenger ribonucleoprotein 1 Homo sapiens 0-4 25416280-2 2015 FMRP is a selective RNA binding protein owing to two central K-homology domains and a C-terminal arginine-glycine-glycine (RGG) box. Glycine 114-121 fragile X messenger ribonucleoprotein 1 Homo sapiens 0-4 21642970-1 2011 We have determined the solution structure of the complex between an arginine-glycine-rich RGG peptide from the human fragile X mental retardation protein (FMRP) and an in vitro-selected guanine-rich (G-rich) sc1 RNA. Glycine 77-84 fragile X messenger ribonucleoprotein 1 Homo sapiens 117-153 24249225-2 2014 FMRP, which is proposed to be involved in the translational regulation of specific neuronal messenger RNA (mRNA) targets, contains an arginine-glycine-glycine (RGG) box RNA binding domain that has been shown to bind with high affinity to G-quadruplex forming mRNA structures. Glycine 143-150 fragile X messenger ribonucleoprotein 1 Homo sapiens 0-4 24249225-2 2014 FMRP, which is proposed to be involved in the translational regulation of specific neuronal messenger RNA (mRNA) targets, contains an arginine-glycine-glycine (RGG) box RNA binding domain that has been shown to bind with high affinity to G-quadruplex forming mRNA structures. Glycine 151-158 fragile X messenger ribonucleoprotein 1 Homo sapiens 0-4 21868366-3 2011 The arginine- and glycine-rich region of FMRP (the RGG box) is unique; it is the high-affinity RNA-binding motif in FMRP and is encoded by exon 15. Glycine 18-25 fragile X messenger ribonucleoprotein 1 Homo sapiens 41-45 21868366-3 2011 The arginine- and glycine-rich region of FMRP (the RGG box) is unique; it is the high-affinity RNA-binding motif in FMRP and is encoded by exon 15. Glycine 18-25 fragile X messenger ribonucleoprotein 1 Homo sapiens 116-120 21642970-1 2011 We have determined the solution structure of the complex between an arginine-glycine-rich RGG peptide from the human fragile X mental retardation protein (FMRP) and an in vitro-selected guanine-rich (G-rich) sc1 RNA. Glycine 77-84 fragile X messenger ribonucleoprotein 1 Homo sapiens 155-159 19396385-3 2008 FMRP has been shown to use its arginine-glycine-glycine rich region (RGG box) to bind to messenger RNAs that form G quadruplex structures. Glycine 40-47 fragile X messenger ribonucleoprotein 1 Homo sapiens 0-4 20541608-2 2010 FMRP has two types of RNA binding domains, two K-homology domains and an arginine-glycine-glycine box domain, and it is proposed to act as a translation regulator of specific messenger RNA. Glycine 82-89 fragile X messenger ribonucleoprotein 1 Homo sapiens 0-4 20541608-2 2010 FMRP has two types of RNA binding domains, two K-homology domains and an arginine-glycine-glycine box domain, and it is proposed to act as a translation regulator of specific messenger RNA. Glycine 90-97 fragile X messenger ribonucleoprotein 1 Homo sapiens 0-4 20541608-8 2010 In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active. Glycine 156-163 fragile X messenger ribonucleoprotein 1 Homo sapiens 24-28 20541608-8 2010 In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active. Glycine 156-163 fragile X messenger ribonucleoprotein 1 Homo sapiens 142-146 20541608-8 2010 In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active. Glycine 156-163 fragile X messenger ribonucleoprotein 1 Homo sapiens 142-146 20541608-8 2010 In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active. Glycine 164-171 fragile X messenger ribonucleoprotein 1 Homo sapiens 24-28 20541608-8 2010 In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active. Glycine 164-171 fragile X messenger ribonucleoprotein 1 Homo sapiens 142-146 20541608-8 2010 In order to assure that FMRP retained activity throughout the process, we used fluorescence spectroscopy to assay the binding activity of the FMRP arginine-glycine-glycine box for the semaphorin 3F mRNA and confirmed that FMRP remained active. Glycine 164-171 fragile X messenger ribonucleoprotein 1 Homo sapiens 142-146 19396385-3 2008 FMRP has been shown to use its arginine-glycine-glycine rich region (RGG box) to bind to messenger RNAs that form G quadruplex structures. Glycine 48-55 fragile X messenger ribonucleoprotein 1 Homo sapiens 0-4 10518318-0 1999 Arginine methylation of a glycine and arginine rich peptide derived from sequences of human FMRP and fibrillarin. Glycine 26-33 fragile X messenger ribonucleoprotein 1 Homo sapiens 92-96 14511639-1 2003 The fragile X mental retardation protein (FMRP) contains three RNA binding domains, two of which the KH2 domain and the C-terminal arginine-glycine-rich (RG-rich) region participate in RNA binding. Glycine 140-147 fragile X messenger ribonucleoprotein 1 Homo sapiens 4-40 14511639-1 2003 The fragile X mental retardation protein (FMRP) contains three RNA binding domains, two of which the KH2 domain and the C-terminal arginine-glycine-rich (RG-rich) region participate in RNA binding. Glycine 140-147 fragile X messenger ribonucleoprotein 1 Homo sapiens 42-46 10973830-8 2000 Binding occurred independently of homoribopolymer binding to the C-terminal arginine-glycine-rich region (RGG box), suggesting that FMRP may bind multiple RNAs simultaneously. Glycine 85-92 fragile X messenger ribonucleoprotein 1 Homo sapiens 132-136 33053340-4 2020 A patient-derived R140Q FMRP point mutation mislocalizes PKA-SPARK activity, whereas deletion of the RNA-binding arginine-glycine-glycine (RGG) box (hFMRP-DeltaRGG) produces fibrillar PKA-SPARK assemblies colocalizing with ribonucleoprotein (RNP) and aggregation (thioflavin T) markers, demonstrating fibrillar partitioning of cytosolic protein aggregates. Glycine 122-129 fragile X messenger ribonucleoprotein 1 Homo sapiens 149-154 33053340-4 2020 A patient-derived R140Q FMRP point mutation mislocalizes PKA-SPARK activity, whereas deletion of the RNA-binding arginine-glycine-glycine (RGG) box (hFMRP-DeltaRGG) produces fibrillar PKA-SPARK assemblies colocalizing with ribonucleoprotein (RNP) and aggregation (thioflavin T) markers, demonstrating fibrillar partitioning of cytosolic protein aggregates. Glycine 130-137 fragile X messenger ribonucleoprotein 1 Homo sapiens 149-154