PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3199133-1 1988 One equivalent of Fe3+ -mesoporphyrin (heme) is coordinated by two axial histidine ligands to a preferred site on histidine-rich glycoprotein (HRG). Histidine 73-82 histidine rich glycoprotein Homo sapiens 114-141 3199133-1 1988 One equivalent of Fe3+ -mesoporphyrin (heme) is coordinated by two axial histidine ligands to a preferred site on histidine-rich glycoprotein (HRG). Histidine 73-82 histidine rich glycoprotein Homo sapiens 143-146 26409900-2 2015 The multidomain arrangement of HPRG comprises two modules at the N-terminus that are homologous to cystatin but void of cysteine proteinase inhibitor function, and a second half consisting of a histidine-proline-rich region (HPRR) located between two proline-rich regions (PRR1 and PRR2), and a C-terminus domain. Histidine 194-203 histidine rich glycoprotein Homo sapiens 31-35 2827651-1 1987 We synthesized a hexapeptide, Gly-His-His-Pro-His-Gly, previously identified as a tandem motif in the histidine-rich glycoprotein (HRG) which has multiple heme-binding sites. Histidine 34-37 histidine rich glycoprotein Homo sapiens 102-129 2827651-1 1987 We synthesized a hexapeptide, Gly-His-His-Pro-His-Gly, previously identified as a tandem motif in the histidine-rich glycoprotein (HRG) which has multiple heme-binding sites. Histidine 34-37 histidine rich glycoprotein Homo sapiens 131-134 2827651-1 1987 We synthesized a hexapeptide, Gly-His-His-Pro-His-Gly, previously identified as a tandem motif in the histidine-rich glycoprotein (HRG) which has multiple heme-binding sites. Histidine 38-41 histidine rich glycoprotein Homo sapiens 102-129 2827651-1 1987 We synthesized a hexapeptide, Gly-His-His-Pro-His-Gly, previously identified as a tandem motif in the histidine-rich glycoprotein (HRG) which has multiple heme-binding sites. Histidine 38-41 histidine rich glycoprotein Homo sapiens 131-134 3986189-8 1985 As with the parent HRG molecule, interaction of the peptide with heme and metals is dependent on pH and intact histidine residues. Histidine 111-120 histidine rich glycoprotein Homo sapiens 19-22 29872214-1 2018 Zinc modulates the biological function of histidine-rich glycoprotein (HRG) through binding to its His-rich region (HRR). Histidine 99-102 histidine rich glycoprotein Homo sapiens 71-74 26409900-3 2015 HPRG has been reported to bind various ligands and to modulate angiogenesis via the histidine residues of the HPRR. Histidine 84-93 histidine rich glycoprotein Homo sapiens 0-4 24970226-7 2014 XAS on HPRG isolated from the AMPD complex showed that zinc is bound to the protein in a dinuclear cluster where each Zn2+ ion is coordinated by three histidine and one heavier ligand, likely sulfur from cysteine. Histidine 151-160 histidine rich glycoprotein Homo sapiens 7-11 19903770-2 2009 The antiangiogenic properties of HRG are mediated via its proteolytically released histidine- and proline-rich (His/Pro-rich) domain. Histidine 83-92 histidine rich glycoprotein Homo sapiens 33-36 19786305-5 2009 Both peptides show a synchrotron radiation (SR) CD-pattern resembling to that of the polyproline II structure, similarly to that of the His-Pro-rich domain of the HRG protein. Histidine 136-139 histidine rich glycoprotein Homo sapiens 163-166 15138272-1 2004 Histidine-rich glycoprotein (HRG) is an alpha2-glycoprotein found in mammalian plasma at high concentrations (approximately 150 microg/ml) and is distinguished by its high content of histidine and proline. Histidine 183-192 histidine rich glycoprotein Homo sapiens 0-27 15269838-1 2004 The anti-angiogenic properties of the histidine-proline-rich (H/P) domain of HPRG have recently been described (Juarez JC, et al. Histidine 38-47 histidine rich glycoprotein Homo sapiens 77-81 15138272-1 2004 Histidine-rich glycoprotein (HRG) is an alpha2-glycoprotein found in mammalian plasma at high concentrations (approximately 150 microg/ml) and is distinguished by its high content of histidine and proline. Histidine 183-192 histidine rich glycoprotein Homo sapiens 29-32 15138272-2 2004 Structurally, HRG is a modular protein consisting of an N-terminal cystatin-like domain (N1N2), a central histidine-rich region (HRR) flanked by proline-rich sequences, and a C-terminal domain. Histidine 106-115 histidine rich glycoprotein Homo sapiens 14-17 1561009-1 1992 Histidine-rich glycoprotein (HRG) is a 74-kD glycoprotein, originally discovered in plasma, which contains an unusually large amount of histidine (13 mol%) and proline (13 mol%). Histidine 136-145 histidine rich glycoprotein Homo sapiens 0-27 9488672-3 1998 Unlike other proteins that interact with heparin via lysine or arginine residues, HPRG relies exclusively on histidine residues for this interaction. Histidine 109-118 histidine rich glycoprotein Homo sapiens 82-86 9488672-11 1998 This provides a mechanism to regulate the function of HPRG (the local pH) and rationalizes the role of its unique, conserved histidine-proline-rich domain. Histidine 125-134 histidine rich glycoprotein Homo sapiens 54-58 7873529-7 1995 Conversely, modification of arginine or histidine residues of HPRG has no effect on complex formation. Histidine 40-49 histidine rich glycoprotein Homo sapiens 62-66 1639922-5 1992 The synthetic peptides represented 1-3 multiple repeat units of the 5-residue sequence (Gly-His-His-Pro-His) found in the C-terminal of HRG. Histidine 92-95 histidine rich glycoprotein Homo sapiens 136-139 1639922-5 1992 The synthetic peptides represented 1-3 multiple repeat units of the 5-residue sequence (Gly-His-His-Pro-His) found in the C-terminal of HRG. Histidine 96-99 histidine rich glycoprotein Homo sapiens 136-139 1639922-5 1992 The synthetic peptides represented 1-3 multiple repeat units of the 5-residue sequence (Gly-His-His-Pro-His) found in the C-terminal of HRG. Histidine 96-99 histidine rich glycoprotein Homo sapiens 136-139 14744774-6 2004 By using truncated versions of HRGP, we demonstrate that the isolated 150 amino acid-residue His/Pro-rich domain, which is also released by spontaneous proteolysis from purified HRGP, mediates the inhibitory effect on chemotaxis. Histidine 93-96 histidine rich glycoprotein Homo sapiens 31-35 14744774-6 2004 By using truncated versions of HRGP, we demonstrate that the isolated 150 amino acid-residue His/Pro-rich domain, which is also released by spontaneous proteolysis from purified HRGP, mediates the inhibitory effect on chemotaxis. Histidine 93-96 histidine rich glycoprotein Homo sapiens 178-182 1561009-1 1992 Histidine-rich glycoprotein (HRG) is a 74-kD glycoprotein, originally discovered in plasma, which contains an unusually large amount of histidine (13 mol%) and proline (13 mol%). Histidine 136-145 histidine rich glycoprotein Homo sapiens 29-32 35224154-3 2022 In many conditions, the histidine-rich region of HRGP strengthens ligand binding following interaction with Zn2+ or exposure to low pH, such as sites of tissue injury or tumor growth. Histidine 24-33 histidine rich glycoprotein Homo sapiens 49-53