PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11781309-8 2002 Furthermore, mutations in this lysine and in a histidine residue that is also predicted to be important for pyridoxal 5"-phosphate binding to Lcb2p also dominantly inactivate SPT similar to the hereditary sensory neuropathy type 1-like mutations in Lcb1p. Histidine 47-56 serine C-palmitoyltransferase LCB1 Saccharomyces cerevisiae S288C 249-254