PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30842276-3 2019 We demonstrate that mda-7/IL-24, administered through a replication incompetent type 5 adenovirus (Ad.mda-7) or with His-MDA-7/IL-24 protein, down-regulates DICER, a critical regulator in miRNA processing. Histidine 117-120 interleukin 24 Homo sapiens 20-25 30842276-3 2019 We demonstrate that mda-7/IL-24, administered through a replication incompetent type 5 adenovirus (Ad.mda-7) or with His-MDA-7/IL-24 protein, down-regulates DICER, a critical regulator in miRNA processing. Histidine 117-120 interleukin 24 Homo sapiens 26-31 30842276-3 2019 We demonstrate that mda-7/IL-24, administered through a replication incompetent type 5 adenovirus (Ad.mda-7) or with His-MDA-7/IL-24 protein, down-regulates DICER, a critical regulator in miRNA processing. Histidine 117-120 interleukin 24 Homo sapiens 121-126 30842276-3 2019 We demonstrate that mda-7/IL-24, administered through a replication incompetent type 5 adenovirus (Ad.mda-7) or with His-MDA-7/IL-24 protein, down-regulates DICER, a critical regulator in miRNA processing. Histidine 117-120 interleukin 24 Homo sapiens 127-132 24282278-7 2014 Recombinant MDA-7/IL-24 (His-MDA-7) induces SARI expression, supporting the involvement of SARI in the MDA-7/IL-24-driven autocrine loop, culminating in antitumor effects. Histidine 25-28 interleukin 24 Homo sapiens 12-17 27940575-3 2017 Either ectopic expression of mda-7/IL-24 or treatment with recombinant His-MDA-7 protein resulted in downregulation of miR-221 and upregulation of p27 and PUMA in a panel of cancer cells, culminating in cell death. Histidine 71-74 interleukin 24 Homo sapiens 75-80 24282278-7 2014 Recombinant MDA-7/IL-24 (His-MDA-7) induces SARI expression, supporting the involvement of SARI in the MDA-7/IL-24-driven autocrine loop, culminating in antitumor effects. Histidine 25-28 interleukin 24 Homo sapiens 18-23 24282278-7 2014 Recombinant MDA-7/IL-24 (His-MDA-7) induces SARI expression, supporting the involvement of SARI in the MDA-7/IL-24-driven autocrine loop, culminating in antitumor effects. Histidine 25-28 interleukin 24 Homo sapiens 29-34 24282278-7 2014 Recombinant MDA-7/IL-24 (His-MDA-7) induces SARI expression, supporting the involvement of SARI in the MDA-7/IL-24-driven autocrine loop, culminating in antitumor effects. Histidine 25-28 interleukin 24 Homo sapiens 29-34 24282278-7 2014 Recombinant MDA-7/IL-24 (His-MDA-7) induces SARI expression, supporting the involvement of SARI in the MDA-7/IL-24-driven autocrine loop, culminating in antitumor effects. Histidine 25-28 interleukin 24 Homo sapiens 109-114 24282278-8 2014 Moreover, His-MDA-7, after binding to its cognate receptors (IL-20R1/IL-20R2 or IL-22R/IL-20R2), induces intracellular signaling by phosphorylation of p38 MAPK, leading to transcription of a family of growth arrest and DNA damage inducible (GADD) genes, culminating in apoptosis. Histidine 10-13 interleukin 24 Homo sapiens 14-19