PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23667485-2	2013	In this study, by screening panels of protein kinase inhibitors and protein phosphatase inhibitors, we identified 5-Iodotubercidin as a strong p53 activator.	5-iodotubercidin	114-130	transformation related protein 53, pseudogene	Mus musculus	143-146	
23667485-4	2013	We found that 5-Iodotubercidin could cause DNA damage, verified by induction of DNA breaks and nuclear foci positive for gammaH2AX and TopBP1, activation of Atm and Chk2, and S15 phosphorylation and up-regulation of p53.	5-iodotubercidin	14-30	transformation related protein 53, pseudogene	Mus musculus	216-219	
23667485-5	2013	As such, 5-Iodotubercidin induces G2 cell cycle arrest in a p53-dependent manner.	5-iodotubercidin	9-25	transformation related protein 53, pseudogene	Mus musculus	60-63	
23667485-8	2013	Moreover, 5-Iodotubercidin showed anti-tumor activity as it could reduce the tumor size in carcinoma xenograft mouse models in p53-dependent and -independent manners.	5-iodotubercidin	10-26	transformation related protein 53, pseudogene	Mus musculus	127-130	
31937797-5	2020	Interestingly, 5-ITu causes sustained accumulation of p53, increases markedly the expression of histone genes and results in reversible upregulation of the pluripotency factor Klf4.	5-iodotubercidin	15-20	transformation related protein 53, pseudogene	Mus musculus	54-57