PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30755485-4 2019 Here, an INSM1 promoter-driven luciferase-based screen revealed that the compound 5"-iodotubercidin suppresses adenosine kinase (ADK), an energy pathway enzyme, and also INSM1 expression and NB tumor growth. 5-iodotubercidin 82-99 INSM transcriptional repressor 1 Homo sapiens 9-14 30755485-4 2019 Here, an INSM1 promoter-driven luciferase-based screen revealed that the compound 5"-iodotubercidin suppresses adenosine kinase (ADK), an energy pathway enzyme, and also INSM1 expression and NB tumor growth. 5-iodotubercidin 82-99 INSM transcriptional repressor 1 Homo sapiens 170-175 30755485-6 2019 We also found that 5"-iodotubercidin inhibits INSM1 expression and induces an intra- and extracellular adenosine imbalance. 5-iodotubercidin 19-36 INSM transcriptional repressor 1 Homo sapiens 46-51 30755485-10 2019 The 5"-iodotubercidin treatment also suppressed beta-catenin, lymphoid enhancer-binding factor 1 (LEF-1), cyclin D1, N-Myc, and INSM1 levels, ultimately leading to apoptosis via caspase-3 and p53 activation. 5-iodotubercidin 4-21 INSM transcriptional repressor 1 Homo sapiens 128-133