PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22889304-6	2012	The thiosemicarbazone-proline conjugates L- and D-Pro-STSC show only moderate cytotoxic potency with IC(50) values of 62 and 75 muM, respectively, in CH1 cells and >100 muM in SW480 cells.	Thiosemicarbazones	4-21	latexin	Homo sapiens	128-131	
25752525-4	2015	Furthermore, one of the thiosemicarbazones was found to be a strong non-competitive inhibitor of alpha-glucosidase (Ki = 9.6 +- 1.6 muM), with an 8-fold increase in activity compared to acarbose (Ki = 77.9 +- 11.4 muM), marketed for the treatment of type-2 diabetes.	Thiosemicarbazones	24-42	latexin	Homo sapiens	132-135	
25752525-4	2015	Furthermore, one of the thiosemicarbazones was found to be a strong non-competitive inhibitor of alpha-glucosidase (Ki = 9.6 +- 1.6 muM), with an 8-fold increase in activity compared to acarbose (Ki = 77.9 +- 11.4 muM), marketed for the treatment of type-2 diabetes.	Thiosemicarbazones	24-42	latexin	Homo sapiens	214-217	
22889304-6	2012	The thiosemicarbazone-proline conjugates L- and D-Pro-STSC show only moderate cytotoxic potency with IC(50) values of 62 and 75 muM, respectively, in CH1 cells and >100 muM in SW480 cells.	Thiosemicarbazones	4-21	latexin	Homo sapiens	172-175	
28891646-7	2017	The resulting boronate/thiosemicarbazone adduct is a medium-sized ring that forms rapidly and irreversibly without any catalyst at low muM concentrations, in neutral buffer, with a rate constant of 9 M-1 s-1 as measured by NMR spectroscopy.	Thiosemicarbazones	23-40	latexin	Homo sapiens	135-138	
27980346-4	2016	The IC50 ranged from 4.7 - 44.1 muM with the complex having an unsubstituted amino group on the thiosemicarbazone being the most active.	Thiosemicarbazones	96-113	latexin	Homo sapiens	32-35