PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31744884-0	2020	Thiosemicarbazones suppress expression of the c-Met oncogene by mechanisms involving lysosomal degradation and intracellular shedding.	Thiosemicarbazones	0-18	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	46-51	
32522525-5	2020	Unexpectedly, novel di-2-pyridylketone thiosemicarbazones that demonstrate marked anti-tumor activity, down-regulate c-MET through their ability to bind intracellular iron and via mechanisms including, down-regulation of MET mRNA, enhanced lysosomal processing and increased metalloprotease-mediated cleavage.	Thiosemicarbazones	39-57	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	117-122	
31744884-6	2020	Confocal microscopy revealed that lysosomotropic agents and the thiosemicarbazones significantly increased co-localization between c-Met and lysosomal-associated membrane protein 2 (LAMP2).	Thiosemicarbazones	64-82	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	131-136	
31744884-13	2020	In summary, the thiosemicarbazones Dp44mT and DpC effectively inhibit oncogenic c-Met through lysosomal degradation and metalloprotease-mediated cleavage.	Thiosemicarbazones	16-34	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	80-85