PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3122755-1 1988 The addition of either recombinant human interleukin 1 (IL1 alpha) or 12-O-tetradecanoyl phorbol-13-acetate (TPA) to cultured rheumatoid synovial cells (RSC) caused dose-related increases in PGE production and cellular fructose 2,6-bisphosphate (Fru-2,6-P2). rsc 153-156 interleukin 1 alpha Homo sapiens 41-65 2117917-3 1990 We report here that the protein kinase C inhibitor staurosporine enhanced the IL-1 alpha-induced increase in [Fru(2,6)P2] and PGE production by RSC, whereas in similar concentrations (3-30 nM) this inhibitor decreased the TPA-induced stimulation of these parameters. rsc 144-147 interleukin 1 alpha Homo sapiens 78-88