PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15631519-3 2005 Iron-loaded Caco-2 cells, with reduced DMT-1 and elevated HFE mRNA levels, down-regulated uptake from ferrous ascorbate and bisglycinate but not from ferric compounds. Ascorbic Acid 102-119 homeostatic iron regulator Homo sapiens 58-61 30059941-8 2018 Genotype specific effect estimates suggested: 1) an inverse relationship between hemoglobin and cadmium levels among HFE H63D homozygotes, and 2) an inverse relationship between vitamin C intake and cadmium levels that strengthens with the number of HFE H63D variant alleles a subject carries. Ascorbic Acid 178-187 homeostatic iron regulator Homo sapiens 250-253 17689879-7 2008 The HFE C282Y mutation likely only became maladaptive in the past several centuries as dietary sources of iron and vitamin C improved in Northern Europe. Ascorbic Acid 115-124 homeostatic iron regulator Homo sapiens 4-7 24036531-4 2013 Hereditary hemochromatosis is a genetic disorder with mutations in the HFE gene, characterized by iron overload (with a reduced vitamin C stability) and with a predominance of affected men. Ascorbic Acid 128-137 homeostatic iron regulator Homo sapiens 71-74