PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23988122-2	2013	The series was derived from a known AR binder, which had previously been shown to form a halogen bond between its bromine atom and the oxygen atom of the Thr-113 side chain of AR.	Bromine	114-121	aldo-keto reductase family 1 member B	Homo sapiens	36-38	
27359042-5	2016	The introduction of Br substituents decreases AR inhibition potency but improves it in the case of AKR1B10.	Bromine	20-22	aldo-keto reductase family 1 member B	Homo sapiens	46-48	
27359042-6	2016	Indeed, the Br atoms in ortho position may impede these drugs to fit into the AR prototypical specificity pocket.	Bromine	12-14	aldo-keto reductase family 1 member B	Homo sapiens	78-80	
23988122-2	2013	The series was derived from a known AR binder, which had previously been shown to form a halogen bond between its bromine atom and the oxygen atom of the Thr-113 side chain of AR.	Bromine	114-121	aldo-keto reductase family 1 member B	Homo sapiens	176-178	
28161411-5	2017	The inhibitor bromine atom can only fit in the wider active site of AKR1B10, mainly because of the native Trp112 side-chain orientation, not possible in AR.	Bromine	14-21	aldo-keto reductase family 1 member B	Homo sapiens	153-155	
21862860-3	2011	In this study a human aldose reductase mutant complexed with a bromine-substituted inhibitor was determined to atomic resolution [Protein Data Bank (PDB) code 3onc].	Bromine	63-70	aldo-keto reductase family 1 member B	Homo sapiens	22-38