PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30991050-0 2019 The in vitro and in vivo depigmenting activity of Coenzyme Q10 through the down-regulation of alpha-MSH signaling pathways and induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated skin keratinocytes. coenzyme Q10 50-62 STAM binding protein Homo sapiens 94-103 30991050-4 2019 It was observed that CoQ10 suppressed p53/POMC, alpha-MSH production as well as inhibited ROS generation in UVA-irradiated keratinocyte HaCaT cells. coenzyme Q10 21-26 STAM binding protein Homo sapiens 48-57 30991050-8 2019 Notably, silencing of Nrf2 (siRNA transfection) significantly diminished CoQ10-mediated anti-melanogenic activity, as evidenced by impaired antioxidant HO-1 gene, uncontrolled ROS generation, and alpha-MSH production following UVA irradiation. coenzyme Q10 73-78 STAM binding protein Homo sapiens 196-205