PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31989689-6	2020	CoQ10 reduced the cell proliferation, histological alterations, and the levels of AFP and TNF-alpha but increased lipids, CH50, and sCD59 in serum.	coenzyme Q10	0-5	tumor necrosis factor	Rattus norvegicus	90-99	
28410798-6	2017	CoQ10 or L-carnitine showed a noticeable effects in improving cardiac functions evidenced reducing serum enzymes as serum interleukin-1 beta (IL-1 beta), tumor necrosis factor alpha (TNF-alpha), leptin, lactate dehydrogenase (LDH), Cardiotrophin-1, Troponin-I and Troponin-T. Also, alleviate oxidative stress, decrease of cardiac Malondialdehyde (MDA), Nitric oxide (NO) and restoring cardiac reduced glutathione levels to normal levels.	coenzyme Q10	0-5	tumor necrosis factor	Rattus norvegicus	154-181	
28410798-6	2017	CoQ10 or L-carnitine showed a noticeable effects in improving cardiac functions evidenced reducing serum enzymes as serum interleukin-1 beta (IL-1 beta), tumor necrosis factor alpha (TNF-alpha), leptin, lactate dehydrogenase (LDH), Cardiotrophin-1, Troponin-I and Troponin-T. Also, alleviate oxidative stress, decrease of cardiac Malondialdehyde (MDA), Nitric oxide (NO) and restoring cardiac reduced glutathione levels to normal levels.	coenzyme Q10	0-5	tumor necrosis factor	Rattus norvegicus	183-192	
34187945-3	2021	The results showed Dox treatment significantly induced GES-1 apoptosis, but preconditioning in GES-1 cells with VC or CoQ10 significantly inhibited the Dox-induced decrease and other harm effects, including the expression and of IkappaKbeta, IkappaBalpha, NF-kappaB/p65 and tumor necrosis factor (TNF-alpha) in GES-1 cells.	coenzyme Q10	118-123	tumor necrosis factor	Rattus norvegicus	297-306	
25753843-7	2015	RESULTS: Our results showed that administration of CoQ10, amlodipine and their combination decreased colon tissue malondialdehyde (MDA), tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), prostaglandin E2 (PGE2), myeloperoxidase (MPO) and heat shock protein (HSP70) levels induced by intracolonic injection of acetic acid and restored many of the colon structure in histological examination.	coenzyme Q10	51-56	tumor necrosis factor	Rattus norvegicus	137-164	
25753843-7	2015	RESULTS: Our results showed that administration of CoQ10, amlodipine and their combination decreased colon tissue malondialdehyde (MDA), tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), prostaglandin E2 (PGE2), myeloperoxidase (MPO) and heat shock protein (HSP70) levels induced by intracolonic injection of acetic acid and restored many of the colon structure in histological examination.	coenzyme Q10	51-56	tumor necrosis factor	Rattus norvegicus	166-175	
34489184-8	2021	Treatment with L-carnitine + Co Q10 ameliorated cognitive impairment and oxidative stress, decreased the brain contents of inflammatory mediators; TNF-alpha, IL-6, and NF-kappabeta elevated AMPK and AKT, as compared to each drug.	coenzyme Q10	29-35	tumor necrosis factor	Rattus norvegicus	147-156	
34187945-5	2021	CoQ10 and VC treatment inhibits Dox-induced gastric mucosal injury by inhibiting the activation of the IkKB/IkappaBalpha/NF-kappaB/p65/TNF-alpha pathway, promoting anti-inflammatory effects of gastric tissue and regulating the composition of the intestinal flora.	coenzyme Q10	0-5	tumor necrosis factor	Rattus norvegicus	135-144	
34400868-6	2021	Consequently, candesartan and/or CoQ10 reversed the oxidative stress and inflammatory changes that occurred following HLI/R as demonstrated by the rise of SOD activity and the decline of MDA, TNF-alpha, and IL-6 skeletal muscle content.	coenzyme Q10	33-38	tumor necrosis factor	Rattus norvegicus	192-201