PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17644511-1 2007 AIMS: This randomized controlled study was designed to determine whether oral coenzyme Q(10) (CoQ(10)) supplementation (100 mg tid) was able to improve extracellular superoxide dismutase (ecSOD) activity and endothelium-dependent (ED) vasodilation in patients with coronary artery disease (CAD). coenzyme Q10 94-101 superoxide dismutase 3 Homo sapiens 152-186 17644511-1 2007 AIMS: This randomized controlled study was designed to determine whether oral coenzyme Q(10) (CoQ(10)) supplementation (100 mg tid) was able to improve extracellular superoxide dismutase (ecSOD) activity and endothelium-dependent (ED) vasodilation in patients with coronary artery disease (CAD). coenzyme Q10 94-101 superoxide dismutase 3 Homo sapiens 188-193 17644511-10 2007 In particular, improvements elicited by CoQ(10) supplementation were remarkable in subjects presenting low initial endothelium-bound ecSOD and thus more prone to oxidative stress. coenzyme Q10 40-47 superoxide dismutase 3 Homo sapiens 133-138 17644511-11 2007 CONCLUSION: Improvements in the ED relaxation and endothelium-bound ecSOD activity might be related to CoQ(10) capability of enhancing endothelial functionality by counteracting nitric oxide oxidation. coenzyme Q10 103-110 superoxide dismutase 3 Homo sapiens 68-73