PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34489184-4	2021	The study aimed to investigate the influence of administration of L-carnitine or/and Co Q10 as theraputic agents against potassium dichromate (PD)-induced brain injury via AMPK/AKT/NF-kappabeta signaling pathway.	coenzyme Q10	85-91	AKT serine/threonine kinase 1	Rattus norvegicus	177-180	
34489184-0	2021	L-carnitine and Co Q10 ameliorate potassium dichromate -induced acute brain injury in rats targeting AMPK/AKT/NF-kappabeta.	coenzyme Q10	16-22	AKT serine/threonine kinase 1	Rattus norvegicus	106-109	
34489184-8	2021	Treatment with L-carnitine + Co Q10 ameliorated cognitive impairment and oxidative stress, decreased the brain contents of inflammatory mediators; TNF-alpha, IL-6, and NF-kappabeta elevated AMPK and AKT, as compared to each drug.	coenzyme Q10	29-35	AKT serine/threonine kinase 1	Rattus norvegicus	199-202	
34489184-10	2021	L-carnitine + Co Q10 play important role in AMPK/AKT/NF-kappabeta pathway that responsible for their antioxidant and anti-inflammatory effects against PD-induced brain injury in rats.	coenzyme Q10	14-20	AKT serine/threonine kinase 1	Rattus norvegicus	49-52	
35239160-11	2022	We also observed that QUIN caused changes in the total ERK and phospho-Akt content, and these effects were partially prevented by CoQ10.	coenzyme Q10	130-135	AKT serine/threonine kinase 1	Rattus norvegicus	71-74	
30668894-8	2019	Oral CoQ10 reduced blood pressure by inducing Akt and nNOS phosphorylation in NTS of fructose-induced hypertensive rats.	coenzyme Q10	5-10	AKT serine/threonine kinase 1	Rattus norvegicus	46-49	
30668894-9	2019	CONCLUSION: Oral CoQ10 decreases blood pressure by negatively regulating fructose-induced NADPH oxidase levels, abolishing ROS generation, reducing p38 phosphorylation, and enhancing the Akt-nNOS pathway in the NTS.	coenzyme Q10	17-22	AKT serine/threonine kinase 1	Rattus norvegicus	187-190	
29115467-14	2018	The above effects of CoQ10 may be mediated by activation of the PTEN/PI3K/AKT pathway.	coenzyme Q10	21-26	AKT serine/threonine kinase 1	Rattus norvegicus	74-77	
29081748-0	2017	CoQ10 Augments Rosuvastatin Neuroprotective Effect in a Model of Global Ischemia via Inhibition of NF-kappaB/JNK3/Bax and Activation of Akt/FOXO3A/Bim Cues.	coenzyme Q10	0-5	AKT serine/threonine kinase 1	Rattus norvegicus	136-139