PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16450077-4 2006 In the present study we show that interaction of the HDL-associated sphingosylphosphorylcholine and sphingosylgalactosyl-3-sulfate (lysosulfatide, LSF) with the G-protein-coupled EDG receptor initiates a signalling cascade that activates the protein kinase Akt and reduces the E-selectin, ICAM-1 and VCAM-1 expression on protein and mRNA level. psychosine-3'-sulfate ester 132-145 AKT serine/threonine kinase 1 Homo sapiens 257-260 11432865-7 2001 Two bioactive lysosphingolipids present in HDL particles, sphingosylphosphorylcholine and lysosulfatide, fully mimicked the survival effect of HDL by blocking the mitochondrial pathway of apoptosis and potently activating Akt. psychosine-3'-sulfate ester 90-103 AKT serine/threonine kinase 1 Homo sapiens 222-225