PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24812692-9 2014 RESULTS: Treatment with NPH improved insulin secretion from beta-cells during the IPGTT and increased pancreatic islet size. Insulin, Isophane 24-27 insulin Homo sapiens 37-44 24843464-2 2011 MATERIALS AND METHODS: We carried out a retrospective study to compare the effects of replacing NPH with detemir in basal-bolus insulin therapy in Japanese patients with type 1 diabetes. Insulin, Isophane 98-101 insulin Homo sapiens 130-137 20678116-1 2010 AIMS: The aim of study was to evaluate the safety and efficacy of insulin detemir as a basal insulin switching from neutral protamine Hagedorn insulin (NPH) and insulin glargine in patients with diabetes on an intensive insulin therapy regimen. Insulin, Isophane 152-155 insulin Homo sapiens 66-73 20678116-5 2010 However, significant improvement was seen only among the patients who had previously used NPH as a basal insulin. Insulin, Isophane 90-93 insulin Homo sapiens 105-112 17565917-5 2007 Treatment with insulin detemir+/-OHA was associated with increases in quality-adjusted life expectancy of 0.309, 0.350, and 0.333 quality-adjusted life-years (QALYs) versus treatment with OHA alone, NPH+/-OHA, and insulin glargine+/-OHA, respectively. Insulin, Isophane 199-202 insulin Homo sapiens 15-22 15498377-5 2004 A group of diabetic rats was then injected with protamine zinc insulin [PZI, 1 - 2 U x kg(-1) x d(-1)] for one week. Insulin, Isophane 72-75 insulin Homo sapiens 63-70 10638500-8 1999 CONCLUSION: In streptozotocin-diabetic rats, normal weight gain can be achieved by treatment with PZI insulin once daily, but attainment of near-normal glucose values requires administration of PZI, NPH, or 70/ 30 insulin twice daily. Insulin, Isophane 98-101 insulin Homo sapiens 102-109 6850362-6 1983 Among these insulin treated groups, the PZI-treated group showed the greatest number of degenerating profiles while the minipump group showed the least. Insulin, Isophane 40-43 insulin Homo sapiens 12-19 31768180-7 2019 Results: Availability in public pharmacies is 63.2% for regular insulin and 68.4% for NPH (isophane) insulin, but differences in availability were observed between levels of care and between regions. Insulin, Isophane 91-99 insulin Homo sapiens 101-108 28230445-12 2017 In general, for both existing and new basal insulin users, higher persistence rate and duration were associated with Medicare versus cash-pay patients, use of insulin pens versus vial/syringe, and use of insulin glargine versus NPH. Insulin, Isophane 228-231 insulin Homo sapiens 44-51