PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18222036-3 2008 Clitocine-induced cell death was characterized with the changes in cell morphology, DNA fragmentation, activation of caspase-3, -8, and -9 (like) activities, poly(ADP-ribose) polymerase (PARP) cleavage, release of cytochrome c (cyt c) into cytosol, and increase of Bax:Bcl-2 ratio. clitocine 0-9 poly(ADP-ribose) polymerase 1 Homo sapiens 158-185 18222036-3 2008 Clitocine-induced cell death was characterized with the changes in cell morphology, DNA fragmentation, activation of caspase-3, -8, and -9 (like) activities, poly(ADP-ribose) polymerase (PARP) cleavage, release of cytochrome c (cyt c) into cytosol, and increase of Bax:Bcl-2 ratio. clitocine 0-9 poly(ADP-ribose) polymerase 1 Homo sapiens 187-191 24563182-5 2014 Biochemical analysis revealed that clitocine-induced tumor growth inhibition is associated with activation of caspases 3, 8 and 9, PARP cleavage, cytochrome c release and Bax, Bak activation, suggesting that clitocine inhibits drug-resistant cancer cell growth through induction of apoptosis. clitocine 35-44 poly(ADP-ribose) polymerase 1 Homo sapiens 131-135