PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28449688-6	2017	In addition, YY-1224 significantly inhibited Abeta (1-42)-induced downregulation of PAF-acetylhydrolase-1 (PAF-AH-1) and peroxisome proliferator-activated receptor gamma (PPARgamma) gene expression.	yy-1224	13-20	peroxisome proliferator activated receptor gamma	Mus musculus	121-169	
28449688-6	2017	In addition, YY-1224 significantly inhibited Abeta (1-42)-induced downregulation of PAF-acetylhydrolase-1 (PAF-AH-1) and peroxisome proliferator-activated receptor gamma (PPARgamma) gene expression.	yy-1224	13-20	peroxisome proliferator activated receptor gamma	Mus musculus	171-180	
28449688-8	2017	YY-1224 significantly attenuated learning impairment, Abeta deposition, and pro-inflammatory microglial activation in APP/PS1 Tg mice, whereas it significantly enhanced PAF-AH and PPARgamma expression.	yy-1224	0-7	peroxisome proliferator activated receptor gamma	Mus musculus	180-189	
28449688-11	2017	CONCLUSIONS: Our results suggest that the protective effects of YY-1224 against Abeta toxicity may be associated with its PAF antagonistic- and PPARgamma agonistic-potential as well as inhibition of the Abeta-mediated pro-inflammatory switch of microglia phenotypes through suppression of COX-2 expression.	yy-1224	64-71	peroxisome proliferator activated receptor gamma	Mus musculus	144-153