PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17963432-0 2007 Megestrol acetate NCD oral suspension--Par Pharmaceutical: megestrol acetate nanocrystal dispersion oral suspension, PAR 100.2, PAR-100.2. Megestrol Acetate 0-17 jumping translocation breakpoint Homo sapiens 39-42 17596111-0 2007 Megestrol acetate NCD oral suspension -- Par Pharmaceutical: megestrol acetate nanocrystal dispersion oral suspension, PAR 100.2, PAR-100.2. Megestrol Acetate 0-17 jumping translocation breakpoint Homo sapiens 41-44 17596111-1 2007 Par Pharmaceutical has developed megestrol acetate (Megace ES) oral suspension for the treatment of anorexia, cachexia and a significant weight loss associated with AIDS. Megestrol Acetate 33-50 jumping translocation breakpoint Homo sapiens 0-3 17596111-1 2007 Par Pharmaceutical has developed megestrol acetate (Megace ES) oral suspension for the treatment of anorexia, cachexia and a significant weight loss associated with AIDS. Megestrol Acetate 52-61 jumping translocation breakpoint Homo sapiens 0-3 17596111-2 2007 Par Pharmaceutical used Elan Corporation"s NanoCrystal Dispersion (NCD) technology to develop an advanced, concentrated formulation of megestrol acetate with improved bioavailability, more rapid onset of action, more convenient dosing and a lower dosing regimen compared with the original marketed formulation of megestrol acetate oral suspension. Megestrol Acetate 135-152 jumping translocation breakpoint Homo sapiens 0-3 17596111-2 2007 Par Pharmaceutical used Elan Corporation"s NanoCrystal Dispersion (NCD) technology to develop an advanced, concentrated formulation of megestrol acetate with improved bioavailability, more rapid onset of action, more convenient dosing and a lower dosing regimen compared with the original marketed formulation of megestrol acetate oral suspension. Megestrol Acetate 313-330 jumping translocation breakpoint Homo sapiens 0-3 17596111-4 2007 The new megestrol acetate NCD formulation represents a line-extension of Par"s megestrol acetate oral suspension (800mg/20mL, Megace O/S) that has been marketed for anorexia, cachexia and AIDS-related weight loss since July 2001. Megestrol Acetate 8-25 jumping translocation breakpoint Homo sapiens 73-76 17596111-10 2007 The NDA for the product was accepted for review by the agency in September 2004, following its submission in June of that year.Par Pharmaceutical commenced the first of two phase III clinical trials of megestrol acetate oral suspension (PAR 100.2) in cancer-induced anorexia in the first quarter of 2006. Megestrol Acetate 202-219 jumping translocation breakpoint Homo sapiens 127-130 17596111-12 2007 The company intends to discuss future development options in this indication with the FDA.New formulations or dosage forms of megestrol acetate concentrated suspension are also in development; Par Pharmaceutical believes these may be available sometime after 2008. Megestrol Acetate 126-143 jumping translocation breakpoint Homo sapiens 193-196 17596111-15 2007 The patent covers more than 30 additional claims in connection with Par Pharmaceutical"s novel formulation of megestrol acetate, and includes claims relating to the advanced formulation of megestrol acetate, specifically to the reduction of the food effect seen with previous formulations of megestrol acetate. Megestrol Acetate 110-127 jumping translocation breakpoint Homo sapiens 68-71 17596111-21 2007 Both companies settled the lawsuit in July 2004 with Par granting a licence to Teva USA for a limited number of units and Par receiving royalties on Teva USA"s net sales of megestrol acetate oral suspension. Megestrol Acetate 173-190 jumping translocation breakpoint Homo sapiens 53-56 17963432-1 2007 Par Pharmaceutical has developed megestrol acetate (Megace ES) oral suspension for the treatment of anorexia, cachexia and a significant weight loss associated with AIDS. Megestrol Acetate 33-50 jumping translocation breakpoint Homo sapiens 0-3 17963432-1 2007 Par Pharmaceutical has developed megestrol acetate (Megace ES) oral suspension for the treatment of anorexia, cachexia and a significant weight loss associated with AIDS. Megestrol Acetate 52-61 jumping translocation breakpoint Homo sapiens 0-3 17963432-2 2007 Par Pharmaceutical used Elan Corporation"s NanoCrystal Dispersion (NCD) technology to develop an advanced, concentrated formulation of megestrol acetate with improved bioavailability, more rapid onset of action, more convenient dosing and a lower dosing regimen compared with the original marketed formulation of megestrol acetate oral suspension. Megestrol Acetate 135-152 jumping translocation breakpoint Homo sapiens 0-3 17963432-2 2007 Par Pharmaceutical used Elan Corporation"s NanoCrystal Dispersion (NCD) technology to develop an advanced, concentrated formulation of megestrol acetate with improved bioavailability, more rapid onset of action, more convenient dosing and a lower dosing regimen compared with the original marketed formulation of megestrol acetate oral suspension. Megestrol Acetate 313-330 jumping translocation breakpoint Homo sapiens 0-3 17963432-4 2007 The new megestrol acetate NCD formulation represents a line-extension of Par"s megestrol acetate oral suspension (800mg/20mL, Megace O/S) that has been marketed for anorexia, cachexia and AIDS-related weight loss since July 2001. Megestrol Acetate 8-25 jumping translocation breakpoint Homo sapiens 73-76 17963432-10 2007 The NDA for the product was accepted for review by the agency in September 2004, following its submission in June of that year.Par Pharmaceutical commenced the first of two phase III clinical trials of megestrol acetate oral suspension (PAR 100.2) in cancer-induced anorexia in the first quarter of 2006. Megestrol Acetate 202-219 jumping translocation breakpoint Homo sapiens 127-130 17963432-12 2007 The company intends to discuss future development options in this indication with the FDA.New formulations or dosage forms of megestrol acetate concentrated suspension are also in development; Par Pharmaceutical believes these may be available sometime after 2008. Megestrol Acetate 126-143 jumping translocation breakpoint Homo sapiens 193-196 17963432-15 2007 The patent covers more than 30 additional claims in connection with Par Pharmaceutical"s novel formulation of megestrol acetate, and includes claims relating to the advanced formulation of megestrol acetate, specifically to the reduction of the food effect seen with previous formulations of megestrol acetate. Megestrol Acetate 110-127 jumping translocation breakpoint Homo sapiens 68-71 17963432-21 2007 Both companies settled the lawsuit in July 2004 with Par granting a licence to Teva USA for a limited number of units and Par receiving royalties on Teva USA"s net sales of megestrol acetate oral suspension. Megestrol Acetate 173-190 jumping translocation breakpoint Homo sapiens 53-56