PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12203099-14	2002	Megestrol acetate administration was associated with profound suppression of ACTH and cortisol levels.	Megestrol Acetate	0-17	proopiomelanocortin	Homo sapiens	77-81	
7907801-6	1993	Treatment of five anorectic patients with megestrol acetate, 480 mg daily for 6 months, reversed only the decrease in CSF beta-endorphin levels but did not normalize the body weight or the fat body mass.	Megestrol Acetate	42-59	proopiomelanocortin	Homo sapiens	122-136	
21850416-6	2012	RESULTS: Forty-five of the 103 patients (43.7%) showed a suppressed adrenal response to the rapid ACTH stimulation test, and the incidence of adrenal suppression was found to be significantly affected by megestrol acetate use (P = 0.035).	Megestrol Acetate	204-221	proopiomelanocortin	Homo sapiens	98-102	
21113214-8	2010	Megestrol acetate did not suppress the secretion of pituitary sex hormones, but in 3 of 10 patients studied was found inhibition of ACTH secretion.	Megestrol Acetate	0-17	proopiomelanocortin	Homo sapiens	132-136	
21113214-11	2010	Megestrol acetate may induce hyperglycaemia and inhibit the secretion of ACTH in some patients.	Megestrol Acetate	0-17	proopiomelanocortin	Homo sapiens	73-77