PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34524495-0	2021	Megestrol acetate is a specific inducer of CYP3A4 mediated by human pregnane X receptor.	Megestrol Acetate	0-17	nuclear receptor subfamily 1 group I member 2	Homo sapiens	68-87	
34524495-5	2021	Competitive ligand binding assay was used to determine the affinity of megestrol acetate toward human pregnane x receptor (hPXR).	Megestrol Acetate	71-88	nuclear receptor subfamily 1 group I member 2	Homo sapiens	102-121	
34524495-5	2021	Competitive ligand binding assay was used to determine the affinity of megestrol acetate toward human pregnane x receptor (hPXR).	Megestrol Acetate	71-88	nuclear receptor subfamily 1 group I member 2	Homo sapiens	123-127	
34524495-11	2021	CONCLUSION: The results suggest that megestrol acetate is a specific inducer of CYP3A4 mediated by hPXR and therefore has the potential to cause drug interactions, especially in the co-administration with drugs that are substrates of CYP3A4.	Megestrol Acetate	37-54	nuclear receptor subfamily 1 group I member 2	Homo sapiens	99-103