PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18812032-9	2008	In DMH-treated rats, the activity of faecal and colonic mucosal bacterial enzymes, such as beta-glucuronidase, beta-galactosidase, beta-glucosidase, nitroreductase, sulfatase and mucinase, were significantly elevated, but in rats supplemented hesperetin along with DMH the activity was significantly lowered (P < 0.05).	1,2-Dimethylhydrazine	3-6	glucuronidase, beta	Rattus norvegicus	91-109	
16850523-1	2007	The aim of the present study was to unravel the chemopreventive effect of luteolin on bacterial enzymes such as beta-glucuronidase and mucinase in a colon carcinogenesis model induced by 1, 2-dimethyl hydrazine (DMH).	1,2-Dimethylhydrazine	187-210	glucuronidase, beta	Rattus norvegicus	112-130	
16850523-1	2007	The aim of the present study was to unravel the chemopreventive effect of luteolin on bacterial enzymes such as beta-glucuronidase and mucinase in a colon carcinogenesis model induced by 1, 2-dimethyl hydrazine (DMH).	1,2-Dimethylhydrazine	212-215	glucuronidase, beta	Rattus norvegicus	112-130	
16850523-6	2007	Colon cancer incidence and the activities of bacterial enzymes beta-glucuronidase (in the proximal colon, distal colon, intestines, liver and colon contents) and mucinase (colon and fecal contents) were significantly increased in DMH -treated rats compared to the control rats.	1,2-Dimethylhydrazine	230-233	glucuronidase, beta	Rattus norvegicus	63-81	
9578735-1	1998	Experiments involving the use of 1,2-dimethylhydrazine-induced colonic tumors in rats showed long-term treatment with a newly synthesized drug EDE-10g to inhibit an enzyme of enteric beta-glucuronidase, to suppress carcinogenesis and to prolong lifespan of animals.	1,2-Dimethylhydrazine	33-54	glucuronidase, beta	Rattus norvegicus	183-201	
9720607-1	1998	In the presence of a known colon carcinogen, 1,2-dimethyl hydrazine (DMH), the activity of beta-glucuronidase was found to be significantly increased in the distal colon, distal intestine, liver and colon contents and the activity of mucinase was increased in both the colon and fecal contents when compared to control rats.	1,2-Dimethylhydrazine	45-67	glucuronidase, beta	Rattus norvegicus	91-109	
9720607-1	1998	In the presence of a known colon carcinogen, 1,2-dimethyl hydrazine (DMH), the activity of beta-glucuronidase was found to be significantly increased in the distal colon, distal intestine, liver and colon contents and the activity of mucinase was increased in both the colon and fecal contents when compared to control rats.	1,2-Dimethylhydrazine	69-72	glucuronidase, beta	Rattus norvegicus	91-109	
16912565-10	2006	The activities of bacterial enzymes beta-glucuronidase (proximal colon, distal colon, intestines, liver and colon contents) and mucinase (colon and fecal contents) were significantly elevated in 1,2-dimethylhydrazine-treated rats as compared with the control rats.	1,2-Dimethylhydrazine	195-216	glucuronidase, beta	Rattus norvegicus	36-54	
16912565-12	2006	Ginger administration to 1,2-dimethylhydrazine-treated rats significantly decreased the incidence and number of tumors as well as the activity of beta-glucuronidase and mucinase.	1,2-Dimethylhydrazine	25-46	glucuronidase, beta	Rattus norvegicus	146-164	
16912565-13	2006	Thus, ginger has a chemopreventive and anticarcinogenic effect against 1,2-dimethylhydrazine-induced colon cancer by virtue of its ability to lower the activities of the microbial enzymes beta-glucuronidase and mucinase.	1,2-Dimethylhydrazine	71-92	glucuronidase, beta	Rattus norvegicus	188-206	
15026282-8	2004	DMH injections significantly elevated both the activities of beta-glucuronidase (distal colon, distal intestine, liver and colon contents) and mucinase (colon and fecal contents) as compared to the control rats.	1,2-Dimethylhydrazine	0-3	glucuronidase, beta	Rattus norvegicus	61-79	
15026282-10	2004	Coconut cake supplementation to DMH-treated rats significantly decreased the incidence and number of tumors as well as the activity of beta-glucuronidase and mucinase.	1,2-Dimethylhydrazine	32-35	glucuronidase, beta	Rattus norvegicus	135-153	
15026282-11	2004	CONCLUSIONS: Coconut cake has a protective effect against DMH induced colon cancer by virtue of its ability to lower the activities of the microbial enzymes beta-glucuronidase and mucinase.	1,2-Dimethylhydrazine	58-61	glucuronidase, beta	Rattus norvegicus	157-175	
14595593-1	2003	The effect of fenugreek seeds on the activities of beta-glucuronidase and mucinase during 1,2-dimethylhydrazine (DMH)-induced colon carcinogenesis in rats was studied.	1,2-Dimethylhydrazine	90-111	glucuronidase, beta	Rattus norvegicus	51-69	
14595593-4	2003	After an experimental period of 30 weeks the activity of beta-glucuronidase significantly increased in the colon, intestine, liver and colon contents in DMH administered rats when compared to an untreated control group.	1,2-Dimethylhydrazine	153-156	glucuronidase, beta	Rattus norvegicus	57-75	
6632908-0	1983	Induction of colon mucosal beta-glucuronidase production as a mechanism for 1,2-dimethylhydrazine colon carcinogenesis.	1,2-Dimethylhydrazine	76-97	glucuronidase, beta	Rattus norvegicus	27-45	
4006053-0	1985	Effect of exogenous beta-glucuronidase on the carcinogenicity of 1,2-dimethylhydrazine in rats: evidence that carcinogenic intermediates form conjugates and act through their subsequent enzymatic release.	1,2-Dimethylhydrazine	65-86	glucuronidase, beta	Rattus norvegicus	20-38	
4006053-5	1985	The broadening of the spectrum of malignant tumours produced in DMH-treated rats by administration of beta-glucuronidase indicates that the carcinogenic effect of DMH may be exerted through formation of comparatively stable conjugates of its metabolites and their enzymic release in target tissues.	1,2-Dimethylhydrazine	64-67	glucuronidase, beta	Rattus norvegicus	102-120	
4006053-5	1985	The broadening of the spectrum of malignant tumours produced in DMH-treated rats by administration of beta-glucuronidase indicates that the carcinogenic effect of DMH may be exerted through formation of comparatively stable conjugates of its metabolites and their enzymic release in target tissues.	1,2-Dimethylhydrazine	163-166	glucuronidase, beta	Rattus norvegicus	102-120	
7306970-16	1981	The effects of selenium and DMH treatments on glutathione peroxidase and beta-glucuronidase activities and on sialic acid are presented.	1,2-Dimethylhydrazine	28-31	glucuronidase, beta	Rattus norvegicus	73-91