PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21679035-0 2011 Reduced tumour progression and angiogenesis in 1,2-dimethylhydrazine mice treated with NS-398 is associated with down-regulation of cyclooxygenase-2 and decreased beta-catenin nuclear localisation. 1,2-Dimethylhydrazine 47-68 prostaglandin-endoperoxide synthase 2 Mus musculus 132-148 17178380-3 2007 We report herein that administration of the selective COX-2 inhibitor, celecoxib, significantly reduces the number of Gr1(+)CD11b(+) immature myeloid suppressor cells (IMSCs) during chemoprevention of 1,2-dimethylhydrazine diHCl-(1,2-DMH-) induction of large intestinal tumors in Swiss mice. 1,2-Dimethylhydrazine 230-237 prostaglandin-endoperoxide synthase 2 Mus musculus 54-59