PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31991138-7	2020	For the beta-arrestin2 assay, fentanyl had full efficacy at the MOP-r whereas morphine and oxycodone were weak with insignificant efficacy at DOP and KOP receptors.	Fentanyl	30-38	arrestin beta 2	Homo sapiens	8-22	
16115983-7	2005	Although beta-arrestin 1 and beta-arrestin 2 are important for these effects induced by opioids with high intrinsic efficacy such as etorphine and fentanyl, morphine tolerance may be mediated mainly via beta-arrestin 2.	Fentanyl	147-155	arrestin beta 2	Homo sapiens	29-44	
27030709-13	2016	In vitro, using beta-arrestin-2/MOP double-transfected human embryonic kidney cells, DAMGO as well as fentanyl lead to a recruitment of beta-arrestin-2 to the membrane followed by a beta-arrestin-2 reappearance in the cytosol and MOP internalization.	Fentanyl	102-110	arrestin beta 2	Homo sapiens	136-151	
27030709-13	2016	In vitro, using beta-arrestin-2/MOP double-transfected human embryonic kidney cells, DAMGO as well as fentanyl lead to a recruitment of beta-arrestin-2 to the membrane followed by a beta-arrestin-2 reappearance in the cytosol and MOP internalization.	Fentanyl	102-110	arrestin beta 2	Homo sapiens	136-151	
9765514-3	1998	Treatment with opioids of high efficacy, either [D-Ala2,N-MePhe4,Gly-ol5]-enkephalin, fentanyl, or sufentanyl, produced a GRK3- and beta-arr 2-dependent reduction in response in <20 min, whereas treatment with the partial agonist morphine produced receptor desensitization at a significantly slower rate.	Fentanyl	86-94	arrestin beta 2	Homo sapiens	132-142