PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16495443-2	2006	Recent work has demonstrated that DHPG-induced LTD recruits at least two signal transduction pathways known to couple to translation, the mitogen-activated protein kinase kinase (MEK)-extracellular signal-regulated kinase (ERK) signaling pathway and the phosphoinositide 3-kinase (PI3K)-Akt-mammalian target of rapamycin (mTOR) signaling pathway.	dhpg	34-38	mitogen-activated protein kinase 1	Homo sapiens	223-226	
16495443-5	2006	We found that both the MEK-ERK and PI3K-mTOR signaling pathways are critical for the DHPG-induced regulation of these translation factors.	dhpg	85-89	mitogen-activated protein kinase 1	Homo sapiens	27-30	
16495443-7	2006	Our results provide direct evidence that cap-dependent translation is engaged during mGluR-LTD and demonstrate that the MEK-ERK and PI3K-mTOR signaling pathways converge to regulate eIF4E activity after induction of DHPG-LTD.	dhpg	216-220	mitogen-activated protein kinase 1	Homo sapiens	124-127