PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21613209-8	2011	Lysates from HEK293 cells overexpressing FN3K or FN3K-RP resulted in phosphorylation of CS-0777 and structurally related molecules but showed little kinase activity for FTY720 and no kinase activity for sphingosine.	Cesium	88-90	fructosamine 3 kinase	Homo sapiens	41-45	
28287856-6	2018	FN3K inhibitor, 1-deoxy-1-morpholinofructose, suppressed only about 20% of CS-0777 phosphorylation activity in human erythrocyte lysate.	Cesium	75-77	fructosamine 3 kinase	Homo sapiens	0-4	
28287856-2	2018	CS-0777, a candidate compound for autoimmune diseases, becomes phosphorylated active metabolite, M1, by fructosamine 3-kinase (FN3K), FN3K-related protein (FN3K-RP); and M1 is reverted back to CS-0777 by alkaline phosphatase (ALP) in the body.	Cesium	0-2	fructosamine 3 kinase	Homo sapiens	104-125	
28287856-2	2018	CS-0777, a candidate compound for autoimmune diseases, becomes phosphorylated active metabolite, M1, by fructosamine 3-kinase (FN3K), FN3K-related protein (FN3K-RP); and M1 is reverted back to CS-0777 by alkaline phosphatase (ALP) in the body.	Cesium	0-2	fructosamine 3 kinase	Homo sapiens	127-131	
28287856-2	2018	CS-0777, a candidate compound for autoimmune diseases, becomes phosphorylated active metabolite, M1, by fructosamine 3-kinase (FN3K), FN3K-related protein (FN3K-RP); and M1 is reverted back to CS-0777 by alkaline phosphatase (ALP) in the body.	Cesium	193-195	fructosamine 3 kinase	Homo sapiens	104-125	
28287856-3	2018	We performed enzyme kinetic analysis of phosphorylation of CS-0777 by FN3K, FN3K-RP, human erythrocytes and human platelets; and dephosphorylation of M1 by various ALP isozymes and human liver, kidney, lung and small intestine microsomes.	Cesium	59-61	fructosamine 3 kinase	Homo sapiens	70-74	
28287856-5	2018	The Michaelis constants of human FN3K, FN3K-RP and erythrocytes for CS-0777 phosphorylation were in the range from 498 muM to 1060 muM.	Cesium	68-70	fructosamine 3 kinase	Homo sapiens	33-37