PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22433854-5	2012	CS exposure substantially and persistently elevated the expression level of Smad7, resulting in a significant reduction of Smad2 phosphorylation (which controls MMP-9 expression) in Fut8(+/-) mice and Fut8-deficient embryonic fibroblast cells.	Cesium	0-2	SMAD family member 2	Mus musculus	123-128	
28602599-8	2017	Additionally, silibinin effectively inhibited CS + LPS-mediated expression of transforming growth factor-beta1 (TGF-beta1) and Smad 2/3 phosphorylation.	Cesium	46-48	SMAD family member 2	Mus musculus	127-135	
28602599-9	2017	Taken together, our data indicate that silibinin effectively inhibits the fibrotic response induced by CS + LPS exposure, possibly via suppression of TGF-beta1/Smad 2/3 signaling, which results in reduced collagen deposition.	Cesium	103-105	SMAD family member 2	Mus musculus	160-168	
28747971-8	2017	PYC markedly reduced the collagen deposition caused by CS+LPS exposure, which was closely involved in TGF-beta1/Smad 2/3 signaling, which is associated with pulmonary fibrotic change.	Cesium	55-57	SMAD family member 2	Mus musculus	112-120	
24508121-11	2014	CONCLUSIONS AND GENERAL SIGNIFICANCE: Altogether, these data suggest that CS initiates EMT through Rac1/Smad2 and Rac1/PI3K/Akt signaling pathway.	Cesium	74-76	SMAD family member 2	Mus musculus	104-109	
20483351-4	2010	CS inhibited S100b-induced TGF-beta1 and fibronectin expression in mouse mesangial cells by suppressing activation of Smad2/3, extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK), and oxidative stress.	Cesium	0-2	SMAD family member 2	Mus musculus	118-125