PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29025711-10 2018 However, Tlr2-/- mice had increased CS-induced emphysema-like alveolar enlargement, apoptosis, and impaired lung function, while these features were reduced in Tlr4-/- mice compared with CS-exposed WT controls. Cesium 36-38 toll-like receptor 2 Mus musculus 9-13 29572385-6 2018 Moreover, we found that PPARgamma activation not only inhibited CS/LPS-induced TLR2/4 expression and miR-27-3p-mediated TLR2/4 signaling cascades involving the nuclear factor-kappaB (NF-kappaB), c-Jun NH2-terminal kinase (JNK)/p38, and Janus kinase-signal transducer and activator of transcription (JAK/STAT) pathways in AMs but also ameliorated CS/LPS-induced AM activation and pulmonary inflammation. Cesium 64-66 toll-like receptor 2 Mus musculus 79-85 26484633-11 2016 CS also activated host peritoneal macrophages, as indicated by increases in phagocytic activity and in TLR-2, CD80 and CD86 expression. Cesium 0-2 toll-like receptor 2 Mus musculus 103-108 16940747-5 2006 CS exposure increased the costimulatory marker expression on DCs, the levels of monocyte chemoattractant protein-1 (MCP-1) and tumor necrosis factor-alpha (TNF-alpha) in bronchoalveolar lavage (BAL) fluid and induced the pulmonary expression of matrix metalloproteinase-12 (MMP-12), TLR4 and TLR2. Cesium 0-2 toll-like receptor 2 Mus musculus 292-296