PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1675281-4	1991	However, when rat femoral head cartilage samples were incubated with 100 ng mL-1 rHu-IL-1 alpha or IL-1 beta for 5 days there was a significant increase in GAG loss from the cartilage into medium, whilst human synovial fluid significantly decreased the loss of GAG from rat cartilage into medium, compared with controls.	Glycosaminoglycans	156-159	L1 cell adhesion molecule	Mus musculus	76-80	
1675281-4	1991	However, when rat femoral head cartilage samples were incubated with 100 ng mL-1 rHu-IL-1 alpha or IL-1 beta for 5 days there was a significant increase in GAG loss from the cartilage into medium, whilst human synovial fluid significantly decreased the loss of GAG from rat cartilage into medium, compared with controls.	Glycosaminoglycans	261-264	L1 cell adhesion molecule	Mus musculus	76-80	
35199120-5	2022	Concurrently, an in vitro model of OA using primary mouse chondrocytes demonstrated that the release of berberine at a concentration as low as 1 mug mL-1 is sufficient to restore the production of sulphated glycosaminoglycans (sGAG) to levels comparable to healthy chondrocytes while avoiding the cytotoxic concentrations (IC50 = 33 mug mL-1) on skin keratinocytes.	Glycosaminoglycans	207-225	L1 cell adhesion molecule	Mus musculus	149-153	
35199120-5	2022	Concurrently, an in vitro model of OA using primary mouse chondrocytes demonstrated that the release of berberine at a concentration as low as 1 mug mL-1 is sufficient to restore the production of sulphated glycosaminoglycans (sGAG) to levels comparable to healthy chondrocytes while avoiding the cytotoxic concentrations (IC50 = 33 mug mL-1) on skin keratinocytes.	Glycosaminoglycans	207-225	L1 cell adhesion molecule	Mus musculus	337-341	
31100859-5	2019	A marine-derived, heparan sulphate-containing glycosaminoglycan extract, isolated from the crab Portunus pelagicus, was identified to inhibit human BACE1 with comparable bioactivity to that of mammalian heparin (IC50 = 1.85 mug mL-1 (R2 = 0.94) and 2.43 mug mL-1 (R2 = 0.93), respectively), while possessing highly attenuated anticoagulant activities.	Glycosaminoglycans	46-63	L1 cell adhesion molecule	Mus musculus	228-232	
31100859-5	2019	A marine-derived, heparan sulphate-containing glycosaminoglycan extract, isolated from the crab Portunus pelagicus, was identified to inhibit human BACE1 with comparable bioactivity to that of mammalian heparin (IC50 = 1.85 mug mL-1 (R2 = 0.94) and 2.43 mug mL-1 (R2 = 0.93), respectively), while possessing highly attenuated anticoagulant activities.	Glycosaminoglycans	46-63	L1 cell adhesion molecule	Mus musculus	258-262