PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17644521-5	2007	This allosteric coupling between RCL positioning and occupancy of the CBG steroid-binding site, which resembles the ligand (glycosamino-glycan)-dependent activation of the thrombin inhibitory serpins heparin cofactor II and anti-thrombin RCLs, ensures both optimal recognition of CBG by target proteinases and efficient release of steroid to sites of action.	Glycosaminoglycans	124-142	coagulation factor II	Rattus norvegicus	172-180	
17644521-5	2007	This allosteric coupling between RCL positioning and occupancy of the CBG steroid-binding site, which resembles the ligand (glycosamino-glycan)-dependent activation of the thrombin inhibitory serpins heparin cofactor II and anti-thrombin RCLs, ensures both optimal recognition of CBG by target proteinases and efficient release of steroid to sites of action.	Glycosaminoglycans	124-142	coagulation factor II	Rattus norvegicus	229-237	
9586576-4	1998	In vitro, the activity of cleavage of fibrinogen by thrombin or prothrombinase activity was more potently depressed by GAG-UTM than by r-UTM, and the generation of activated protein C by TM-thrombin complex was accelerated by GAG modification.	Glycosaminoglycans	119-122	coagulation factor II	Rattus norvegicus	52-60	
7117492-0	1982	Effect of thrombin on glycosaminoglycans in fibroblast cultures.	Glycosaminoglycans	22-40	coagulation factor II	Rattus norvegicus	10-18	
9483172-2	1997	In in vitro studies, the prolongation of thrombin clotting time (TCT) by these glycosaminoglycans was completely neutralized by PS, whereas activated partial thromboplastin time (APTT) was relatively resistant to neutralization.	Glycosaminoglycans	79-97	coagulation factor II	Rattus norvegicus	41-49	
8446935-1	1993	The mode of action of glycosaminoglycans (GAGs) towards thrombus formation in a rat arteriovenous shunt was studied by simultaneous examination of thrombus weight, platelet consumption and thrombin generation during 45 min of blood circulation.	Glycosaminoglycans	22-40	coagulation factor II	Rattus norvegicus	189-197	
720453-8	1978	The supernatant of the fibrinogen-thrombin-reaction, separated after 3 hours, likewise increased glucose consumption, GAG and hyaluronic acid concentration possibly due to effects of the fibrinopeptides A or B.	Glycosaminoglycans	118-121	coagulation factor II	Rattus norvegicus	34-42